Long-term survival of pancreatic islet allografts in pancreatectomized dogs

Rodolfo Alejandro, R. Cutfield, F. L. Shienvold

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The present study was made possible by the development of a procedure to isolate islets from a single canine pancreas in sufficient quantities and prurity to provide autoengraftment after portal vein injection in totally pancreatectomized beagle dogs. The refinement of the technique with islet autografts has prompted this report of the immunosuppressive effectiveness of cyclosporine A (CsA) with islet allografts. We also asked whether interruption of CsA administration would still be associated with long-term allograft acceptance as previously shown in rodents and rabbits.

Original languageEnglish
Pages (from-to)829-830
Number of pages2
JournalTransplantation Proceedings
Volume18
Issue number4
StatePublished - Jan 1 1986

Fingerprint

Islets of Langerhans
Cyclosporine
Allografts
Dogs
Autografts
Immunosuppressive Agents
Portal Vein
Canidae
Pancreas
Rodentia
Rabbits
Injections

ASJC Scopus subject areas

  • Surgery
  • Transplantation

Cite this

Long-term survival of pancreatic islet allografts in pancreatectomized dogs. / Alejandro, Rodolfo; Cutfield, R.; Shienvold, F. L.

In: Transplantation Proceedings, Vol. 18, No. 4, 01.01.1986, p. 829-830.

Research output: Contribution to journalArticle

Alejandro, Rodolfo ; Cutfield, R. ; Shienvold, F. L. / Long-term survival of pancreatic islet allografts in pancreatectomized dogs. In: Transplantation Proceedings. 1986 ; Vol. 18, No. 4. pp. 829-830.
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