Abstract
Purpose: To evaluate long-term follow-up of Intacs microthin prescription inserts (Addition Technology, Inc, Fremont, California, USA) for the management of keratoconus. Design: A long-term (five years) retrospective, follow-up study. Methods: Seventeen eyes of 15 patients with keratoconus ages 24 to 52 years (mean age ± standard deviation [SD], 34.0 ± 10.5 years) who had completed five years of follow-up (mean follow-up ± SD, 67.2 ± 7.5 months; range, 58 to 78 months) were included. Two Intacs segments of 0.45-mm thickness were inserted in the cornea of each eye, aiming at embracing the keratoconus area to try to achieve maximal flattening. Results: No late postoperative complications occurred in this series of patients. At five years, the spherical equivalent error was statistically significantly reduced (pre-Intacs, mean ± SD -5.54 ± 5.02 diopters [D]; range, -12.50 to 3.63 D; -3.02 ± 2.65 D; range, -8.25 to 1.88 D) (P = .01). Pre-Intacs uncorrected visual acuity (UCVA) was 20/50 or worse in all eyes (range, counting fingers to 20/50), whereas, at the last follow-up examination, 10 (59%) of 17 eyes had UCVA of 20/50 or better (range, counting fingers to 20/32). Six eyes (35%) maintained the pre-Intacs best spectacle-corrected visual acuity (BSCVA) and one eye lost 3 lines of BSCVA, whereas the rest of the 10 eyes (59%) experienced a gain of one up to 8 lines. Conclusions: After five years, intracorneal ring segments implantation improved UCVA, BSCVA, and refraction in the majority of the keratoconus patients. There was no evidence of progressive sight-threatening complications in this study.
| Original language | English |
|---|---|
| Journal | American Journal of Ophthalmology |
| Volume | 143 |
| Issue number | 2 |
| DOIs | |
| State | Published - Feb 1 2007 |
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ASJC Scopus subject areas
- Ophthalmology
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Long-term Follow-up of Intacs in Keratoconus. / Kymionis, George D.; Siganos, Charalambos S.; Tsiklis, Nikolaos S.; Anastasakis, Anastasios; Yoo, Sonia H; Pallikaris, Aristofanis I.; Astyrakakis, Nikolaos; Pallikaris, Ioannis G.
In: American Journal of Ophthalmology, Vol. 143, No. 2, 01.02.2007.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Long-term Follow-up of Intacs in Keratoconus
AU - Kymionis, George D.
AU - Siganos, Charalambos S.
AU - Tsiklis, Nikolaos S.
AU - Anastasakis, Anastasios
AU - Yoo, Sonia H
AU - Pallikaris, Aristofanis I.
AU - Astyrakakis, Nikolaos
AU - Pallikaris, Ioannis G.
PY - 2007/2/1
Y1 - 2007/2/1
N2 - Purpose: To evaluate long-term follow-up of Intacs microthin prescription inserts (Addition Technology, Inc, Fremont, California, USA) for the management of keratoconus. Design: A long-term (five years) retrospective, follow-up study. Methods: Seventeen eyes of 15 patients with keratoconus ages 24 to 52 years (mean age ± standard deviation [SD], 34.0 ± 10.5 years) who had completed five years of follow-up (mean follow-up ± SD, 67.2 ± 7.5 months; range, 58 to 78 months) were included. Two Intacs segments of 0.45-mm thickness were inserted in the cornea of each eye, aiming at embracing the keratoconus area to try to achieve maximal flattening. Results: No late postoperative complications occurred in this series of patients. At five years, the spherical equivalent error was statistically significantly reduced (pre-Intacs, mean ± SD -5.54 ± 5.02 diopters [D]; range, -12.50 to 3.63 D; -3.02 ± 2.65 D; range, -8.25 to 1.88 D) (P = .01). Pre-Intacs uncorrected visual acuity (UCVA) was 20/50 or worse in all eyes (range, counting fingers to 20/50), whereas, at the last follow-up examination, 10 (59%) of 17 eyes had UCVA of 20/50 or better (range, counting fingers to 20/32). Six eyes (35%) maintained the pre-Intacs best spectacle-corrected visual acuity (BSCVA) and one eye lost 3 lines of BSCVA, whereas the rest of the 10 eyes (59%) experienced a gain of one up to 8 lines. Conclusions: After five years, intracorneal ring segments implantation improved UCVA, BSCVA, and refraction in the majority of the keratoconus patients. There was no evidence of progressive sight-threatening complications in this study.
AB - Purpose: To evaluate long-term follow-up of Intacs microthin prescription inserts (Addition Technology, Inc, Fremont, California, USA) for the management of keratoconus. Design: A long-term (five years) retrospective, follow-up study. Methods: Seventeen eyes of 15 patients with keratoconus ages 24 to 52 years (mean age ± standard deviation [SD], 34.0 ± 10.5 years) who had completed five years of follow-up (mean follow-up ± SD, 67.2 ± 7.5 months; range, 58 to 78 months) were included. Two Intacs segments of 0.45-mm thickness were inserted in the cornea of each eye, aiming at embracing the keratoconus area to try to achieve maximal flattening. Results: No late postoperative complications occurred in this series of patients. At five years, the spherical equivalent error was statistically significantly reduced (pre-Intacs, mean ± SD -5.54 ± 5.02 diopters [D]; range, -12.50 to 3.63 D; -3.02 ± 2.65 D; range, -8.25 to 1.88 D) (P = .01). Pre-Intacs uncorrected visual acuity (UCVA) was 20/50 or worse in all eyes (range, counting fingers to 20/50), whereas, at the last follow-up examination, 10 (59%) of 17 eyes had UCVA of 20/50 or better (range, counting fingers to 20/32). Six eyes (35%) maintained the pre-Intacs best spectacle-corrected visual acuity (BSCVA) and one eye lost 3 lines of BSCVA, whereas the rest of the 10 eyes (59%) experienced a gain of one up to 8 lines. Conclusions: After five years, intracorneal ring segments implantation improved UCVA, BSCVA, and refraction in the majority of the keratoconus patients. There was no evidence of progressive sight-threatening complications in this study.
UR - http://www.scopus.com/inward/record.url?scp=33846397431&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33846397431&partnerID=8YFLogxK
U2 - 10.1016/j.ajo.2006.10.041
DO - 10.1016/j.ajo.2006.10.041
M3 - Article
C2 - 17184717
AN - SCOPUS:33846397431
VL - 143
JO - American Journal of Ophthalmology
JF - American Journal of Ophthalmology
SN - 0002-9394
IS - 2
ER -