Localization of urinary tract infection in patients with spinal cord injury

Thomas Hooton, E. J. O'Shaughnessy, D. Clowers, L. Mack, D. D. Cardenas, W. E. Stamm

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

The site of urinary tract infection (UTI) was localized in asymptomatic bacteriuric patients with spinal cord injury who underwent intermittent bladder catheterization by the bladder washout (BWO) test, antibody-coated bacteria (ACB) test, quantitative urinary leukocyte count, ultrasonography, and excretory urography. Thirty-two (43%) of 74 UTIs were localized by BWO to the upper tract and 42 (57%) to the lower tract. Sensitivity of the ACB test in detecting upper UTI as defined by BWO was 0.28, and specificity was 0.86. The median urinary leukocyte count in 22 BWO-positive infections tested was 420 vs. 94 in 24 BWO-negative infections (P = .01). Patients with polymicrobic infections or with upper tract abnormalities, as detected by ultrasound or excretory urography, were more likely to have BWO-positive infections. We conclude that negative BWOs are usually associated with negative ACB tests in this population, but further comparisons of both tests with ureteral catheterization are needed to clarify the meaning of results in either assay.

Original languageEnglish
Pages (from-to)85-91
Number of pages7
JournalJournal of Infectious Diseases
Volume150
Issue number1
StatePublished - Sep 20 1984
Externally publishedYes

Fingerprint

Spinal Cord Injuries
Urinary Tract Infections
Urinary Bladder
Urinary Antibody Coated Bacteria Test
Urography
Infection
Leukocyte Count
Urinary Catheterization
Bacteria
Antibodies
Catheterization
Ultrasonography
Population

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Immunology

Cite this

Hooton, T., O'Shaughnessy, E. J., Clowers, D., Mack, L., Cardenas, D. D., & Stamm, W. E. (1984). Localization of urinary tract infection in patients with spinal cord injury. Journal of Infectious Diseases, 150(1), 85-91.

Localization of urinary tract infection in patients with spinal cord injury. / Hooton, Thomas; O'Shaughnessy, E. J.; Clowers, D.; Mack, L.; Cardenas, D. D.; Stamm, W. E.

In: Journal of Infectious Diseases, Vol. 150, No. 1, 20.09.1984, p. 85-91.

Research output: Contribution to journalArticle

Hooton, T, O'Shaughnessy, EJ, Clowers, D, Mack, L, Cardenas, DD & Stamm, WE 1984, 'Localization of urinary tract infection in patients with spinal cord injury', Journal of Infectious Diseases, vol. 150, no. 1, pp. 85-91.
Hooton T, O'Shaughnessy EJ, Clowers D, Mack L, Cardenas DD, Stamm WE. Localization of urinary tract infection in patients with spinal cord injury. Journal of Infectious Diseases. 1984 Sep 20;150(1):85-91.
Hooton, Thomas ; O'Shaughnessy, E. J. ; Clowers, D. ; Mack, L. ; Cardenas, D. D. ; Stamm, W. E. / Localization of urinary tract infection in patients with spinal cord injury. In: Journal of Infectious Diseases. 1984 ; Vol. 150, No. 1. pp. 85-91.
@article{f3485f71e53e480eb7718ecf8fb4e6b7,
title = "Localization of urinary tract infection in patients with spinal cord injury",
abstract = "The site of urinary tract infection (UTI) was localized in asymptomatic bacteriuric patients with spinal cord injury who underwent intermittent bladder catheterization by the bladder washout (BWO) test, antibody-coated bacteria (ACB) test, quantitative urinary leukocyte count, ultrasonography, and excretory urography. Thirty-two (43{\%}) of 74 UTIs were localized by BWO to the upper tract and 42 (57{\%}) to the lower tract. Sensitivity of the ACB test in detecting upper UTI as defined by BWO was 0.28, and specificity was 0.86. The median urinary leukocyte count in 22 BWO-positive infections tested was 420 vs. 94 in 24 BWO-negative infections (P = .01). Patients with polymicrobic infections or with upper tract abnormalities, as detected by ultrasound or excretory urography, were more likely to have BWO-positive infections. We conclude that negative BWOs are usually associated with negative ACB tests in this population, but further comparisons of both tests with ureteral catheterization are needed to clarify the meaning of results in either assay.",
author = "Thomas Hooton and O'Shaughnessy, {E. J.} and D. Clowers and L. Mack and Cardenas, {D. D.} and Stamm, {W. E.}",
year = "1984",
month = "9",
day = "20",
language = "English",
volume = "150",
pages = "85--91",
journal = "Journal of Infectious Diseases",
issn = "0022-1899",
publisher = "Oxford University Press",
number = "1",

}

TY - JOUR

T1 - Localization of urinary tract infection in patients with spinal cord injury

AU - Hooton, Thomas

AU - O'Shaughnessy, E. J.

AU - Clowers, D.

AU - Mack, L.

AU - Cardenas, D. D.

AU - Stamm, W. E.

PY - 1984/9/20

Y1 - 1984/9/20

N2 - The site of urinary tract infection (UTI) was localized in asymptomatic bacteriuric patients with spinal cord injury who underwent intermittent bladder catheterization by the bladder washout (BWO) test, antibody-coated bacteria (ACB) test, quantitative urinary leukocyte count, ultrasonography, and excretory urography. Thirty-two (43%) of 74 UTIs were localized by BWO to the upper tract and 42 (57%) to the lower tract. Sensitivity of the ACB test in detecting upper UTI as defined by BWO was 0.28, and specificity was 0.86. The median urinary leukocyte count in 22 BWO-positive infections tested was 420 vs. 94 in 24 BWO-negative infections (P = .01). Patients with polymicrobic infections or with upper tract abnormalities, as detected by ultrasound or excretory urography, were more likely to have BWO-positive infections. We conclude that negative BWOs are usually associated with negative ACB tests in this population, but further comparisons of both tests with ureteral catheterization are needed to clarify the meaning of results in either assay.

AB - The site of urinary tract infection (UTI) was localized in asymptomatic bacteriuric patients with spinal cord injury who underwent intermittent bladder catheterization by the bladder washout (BWO) test, antibody-coated bacteria (ACB) test, quantitative urinary leukocyte count, ultrasonography, and excretory urography. Thirty-two (43%) of 74 UTIs were localized by BWO to the upper tract and 42 (57%) to the lower tract. Sensitivity of the ACB test in detecting upper UTI as defined by BWO was 0.28, and specificity was 0.86. The median urinary leukocyte count in 22 BWO-positive infections tested was 420 vs. 94 in 24 BWO-negative infections (P = .01). Patients with polymicrobic infections or with upper tract abnormalities, as detected by ultrasound or excretory urography, were more likely to have BWO-positive infections. We conclude that negative BWOs are usually associated with negative ACB tests in this population, but further comparisons of both tests with ureteral catheterization are needed to clarify the meaning of results in either assay.

UR - http://www.scopus.com/inward/record.url?scp=0021245484&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021245484&partnerID=8YFLogxK

M3 - Article

C2 - 6379063

AN - SCOPUS:0021245484

VL - 150

SP - 85

EP - 91

JO - Journal of Infectious Diseases

JF - Journal of Infectious Diseases

SN - 0022-1899

IS - 1

ER -