Abstract
The gene for human P45017α (CYP17) was previously mapped to chromosome 10 through analysis of somatic cell hybrids. Using a modified procedure of fluorescence in situ hybridization, this gene has now been visualized on simultaneously banded chromosomes and localized to a specific subband of chromosome 10 at q24.3. This precise assignment may facilitate the understanding of the molecular basis of 17α-hydroxylase/17,20-lyase deficiency and the evolution of the CYP superfamily of genes.
Original language | English (US) |
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Pages (from-to) | 1110-1111 |
Number of pages | 2 |
Journal | Genomics |
Volume | 14 |
Issue number | 4 |
DOIs | |
State | Published - Dec 1992 |
Externally published | Yes |
ASJC Scopus subject areas
- Genetics