TY - JOUR
T1 - Local wound care and topical management of hidradenitis suppurativa
AU - Alavi, Afsaneh
AU - Kirsner, Robert
PY - 2015/11/1
Y1 - 2015/11/1
N2 - Hidradenitis suppurativa (HS) is a chronic, recurrent, debilitating disease predominantly involving apocrine gland-bearing skin. The folliculoinfundibular dysfunction and an aberrant cutaneous immune response to commensal bacteria are recognized as potential contributors. Topical antibiotics, such as clindamycin, and keratolytic agents have been used in the management of early stages of HS. Proper wound care is a key part of management, particularly in patients with advanced HS. The evidence for the optimal topical therapy or optimal local wound care is limited. As such, a multidisciplinary approach is necessary to address all aspects of HS, including topical therapy, systemic therapy, and proper wound care. The focus of this paper is to review the evidence for the topical management and local wound care strategies in patients with HS.
AB - Hidradenitis suppurativa (HS) is a chronic, recurrent, debilitating disease predominantly involving apocrine gland-bearing skin. The folliculoinfundibular dysfunction and an aberrant cutaneous immune response to commensal bacteria are recognized as potential contributors. Topical antibiotics, such as clindamycin, and keratolytic agents have been used in the management of early stages of HS. Proper wound care is a key part of management, particularly in patients with advanced HS. The evidence for the optimal topical therapy or optimal local wound care is limited. As such, a multidisciplinary approach is necessary to address all aspects of HS, including topical therapy, systemic therapy, and proper wound care. The focus of this paper is to review the evidence for the topical management and local wound care strategies in patients with HS.
KW - Clindamycin
KW - Hidradenitis suppurativa
KW - NPWT
KW - Resorcinol
KW - Retinoid
KW - Topical treatments
UR - http://www.scopus.com/inward/record.url?scp=84944047779&partnerID=8YFLogxK
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U2 - 10.1016/j.jaad.2015.07.048
DO - 10.1016/j.jaad.2015.07.048
M3 - Article
C2 - 26470618
AN - SCOPUS:84944047779
VL - 73
SP - S55-S61
JO - Journal of the American Academy of Dermatology
JF - Journal of the American Academy of Dermatology
SN - 0190-9622
IS - 5
ER -