TY - JOUR
T1 - Local recurrence of soft-tissue sarcoma
T2 - issues in imaging surveillance strategy
AU - Ezuddin, Nisreen S.
AU - Pretell-Mazzini, Juan
AU - Yechieli, Raphael L.
AU - Kerr, Darcy A.
AU - Wilky, Breelyn A.
AU - Subhawong, Ty K.
N1 - Funding Information:
Funding/disclosures The authors Nisreen S. Ezuddin, Juan Pretell-Mazzini, Raphael L. Yechieli, and Darcy Kerr have received no funding for the preparation of this manuscript. Breelyn A. Wilky is currently receiving research funding from Merck & Co., Inc. Ty K. Subhawong has received honoraria from iiCME for speaking activities unrelated to the preparation of this manuscript.
Publisher Copyright:
© 2018, ISS.
PY - 2018/12/1
Y1 - 2018/12/1
N2 - Soft-tissue sarcomas pose diagnostic and therapeutic challenges to physicians, owing to the large number of subtypes, aggressive tumor biology, lack of consensus on management, and controversy surrounding interval and duration of surveillance scans. Advances in multidisciplinary management have improved the care of sarcoma patients, but controversy remains regarding strategies for surveillance following definitive local control. This review provides an updated, comprehensive overview of the current understanding of the risk of local recurrence of soft-tissue sarcoma, by examining the literature based on features such as histological type and grade, tumor size, and resection margin status, with the aim of helping clinicians, surgeons, and radiologists to develop a tailored approach to local imaging surveillance.
AB - Soft-tissue sarcomas pose diagnostic and therapeutic challenges to physicians, owing to the large number of subtypes, aggressive tumor biology, lack of consensus on management, and controversy surrounding interval and duration of surveillance scans. Advances in multidisciplinary management have improved the care of sarcoma patients, but controversy remains regarding strategies for surveillance following definitive local control. This review provides an updated, comprehensive overview of the current understanding of the risk of local recurrence of soft-tissue sarcoma, by examining the literature based on features such as histological type and grade, tumor size, and resection margin status, with the aim of helping clinicians, surgeons, and radiologists to develop a tailored approach to local imaging surveillance.
KW - Imaging surveillance
KW - Local recurrence
KW - MRI
KW - Musculoskeletal sarcoma
KW - Soft-tissue sarcoma
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U2 - 10.1007/s00256-018-2965-x
DO - 10.1007/s00256-018-2965-x
M3 - Review article
C2 - 29785452
AN - SCOPUS:85047228335
VL - 47
SP - 1595
EP - 1606
JO - Skeletal Radiology
JF - Skeletal Radiology
SN - 0364-2348
IS - 12
ER -