Local gangrene: A complication of peripheral pitressin therapy for bleeding esophageal varices

Richard A. Greenwald, Owen J. Rheingold, Roberto O. Chiprut, Arvey I. Rogers

Research output: Contribution to journalArticle

38 Scopus citations

Abstract

Two patients developed local gangrene after subcutaneous infiltration of vasopressin (Pitressin, Parke, Davis & Company, Detroit, Mich.) utilized for the control of bleeding from esophageal varices. In the 1st patient, ischemic gangrene resulted in transmetatarsal amputation and also necessitated skin grafts on the forearm. The 2nd patient developed gangrene and clostridial sepsis and expired. The effects of systemically administered Pitressin are reviewed and suggestions to prevent local necrosis are presented.

Original languageEnglish (US)
Pages (from-to)744-746
Number of pages3
JournalGastroenterology
Volume74
Issue number4
DOIs
StatePublished - Apr 1978

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

Fingerprint Dive into the research topics of 'Local gangrene: A complication of peripheral pitressin therapy for bleeding esophageal varices'. Together they form a unique fingerprint.

  • Cite this