Liver Transplantation for Hepatocellular Carcinoma

Lessons Learned and Future Directions

David M. Levi, Seigo Nishida

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The past 2 decades have witnessed an exponential increase in the incidence of hepatocellular carcinoma (HCC) in the United States and, concurrently, the development of liver transplantation as an effective modality in its treatment. "Early" HCC has been defined, allowing patients with unresectable HCC to be granted priority for transplant over the past decade. This situation has produced a dramatic increase in the number of transplants for HCC. The challenge has been how to expand the indications of liver transplant for HCC with improved cancer-free survival and fewer transplant-related complications without adversely affecting non-HCC transplant candidates.

Original languageEnglish
Pages (from-to)717-725
Number of pages9
JournalClinics in Liver Disease
Volume15
Issue number4
DOIs
StatePublished - Nov 1 2011

Fingerprint

Liver Transplantation
Hepatocellular Carcinoma
Transplants
Direction compound
Carcinoma
Survival
Liver
Incidence
Neoplasms
Therapeutics

Keywords

  • Adoptive immunotherapy
  • Bridge therapy
  • Cirrhosis
  • Downstaging
  • Hepatocellular carcinoma
  • Liver transplant
  • Natural killer cells
  • Recurrence

ASJC Scopus subject areas

  • Hepatology

Cite this

Liver Transplantation for Hepatocellular Carcinoma : Lessons Learned and Future Directions. / Levi, David M.; Nishida, Seigo.

In: Clinics in Liver Disease, Vol. 15, No. 4, 01.11.2011, p. 717-725.

Research output: Contribution to journalArticle

Levi, David M. ; Nishida, Seigo. / Liver Transplantation for Hepatocellular Carcinoma : Lessons Learned and Future Directions. In: Clinics in Liver Disease. 2011 ; Vol. 15, No. 4. pp. 717-725.
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