Liver disease in the elderly

A. Regev, Eugene R Schiff

Research output: Contribution to journalArticle

45 Citations (Scopus)

Abstract

Despite several morphologic and functional changes that have been described in the aging liver, most relevant studies fail to identify a significant age-related deficit in liver function in humans. One of the important age-related changes is a decrease in regenerative capacity, which may partly explain the impaired recovery after severe viral and toxic injury in the elderly. Nevertheless, livers from older subjects are used successfully for transplantation. Substantial morbidity and mortality in the elderly is attributable to liver diseases, and the number of patients older than 65 years of age with chronic liver disease is increasing rapidly. Although there are no liver diseases specific to advanced age, the presentation, clinical course and management of liver diseases in the elderly may differ in important respects from those of younger individuals.

Original languageEnglish
Pages (from-to)547-563
Number of pages17
JournalGastroenterology Clinics of North America
Volume30
Issue number2
DOIs
StatePublished - Jul 3 2001

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Liver Diseases
Liver
Poisons
Chronic Disease
Transplantation
Morbidity
Mortality
Wounds and Injuries

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Liver disease in the elderly. / Regev, A.; Schiff, Eugene R.

In: Gastroenterology Clinics of North America, Vol. 30, No. 2, 03.07.2001, p. 547-563.

Research output: Contribution to journalArticle

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