TY - JOUR
T1 - Liver biopsy interpretation for causes of late liver allograft dysfunction
AU - Banff Working Group
AU - Demetris, A. J.
AU - Demetris, Anthony J.
AU - Adeyi, Oyedele
AU - Bellamy, Chris O.C.
AU - Clouston, Andrew
AU - Charlotte, Frederic
AU - Czaja, Albert
AU - Daskal, Ierachmiel
AU - El-Monayeri, Magda S.
AU - Fontes, Paulo
AU - Fung, John
AU - Gridelli, Bruno
AU - Guido, Maria
AU - Haga, Hironori
AU - Hart, John
AU - Honsova, Eva
AU - Hubscher, Stefan
AU - Itoh, Tomoo
AU - Jhala, Nirag
AU - Jungmann, Patricia
AU - Khettry, Urmila
AU - Lassman, Charles
AU - Ligato, Saverio
AU - Lunz, John G.
AU - Marcos, Amadeo
AU - Minervini, Marta Ida
AU - Molne, Johan
AU - Nalesnik, Mike
AU - Nasser, Imad
AU - Neil, Desley
AU - Ochoa, Erin
AU - Pappo, Orit
AU - Randhawa, Parmjeet
AU - Reinholt, Finn P.
AU - Ruiz, Phil
AU - Sebagh, Mylene
AU - Spada, Marco
AU - Sonzogni, Aurelio
AU - Tsamandas, Athanassios C.
AU - Wernerson, Annika
AU - Wu, Tong
AU - Yilmaz, Funda
PY - 2006/8/1
Y1 - 2006/8/1
N2 - Evaluation of needle biopsies and extensive clinicopathological correlation play an important role in the determination of liver allograft dysfunction occurring more than 1 year after transplantation. Interpretation of these biopsies can be quite difficult because of the high incidence of recurrent diseases that show histopathological, clinical, and serological features that overlap with each other and with rejection. Also, more than one insult can contribute to allograft injury. In an attempt to enable centers to compare and pool results, improve therapy, and better understand pathophysiological disease mechanisms, the Banff Working Group on Liver Allograft Pathology herein proposes a set of consensus criteria for the most common and problematic causes of late liver allograft dysfunction, including late-onset acute and chronic rejection, recurrent and new-onset viral and autoimmune hepatitis, biliary strictures, and recurrent primary biliary cirrhosis and primary sclerosing cholangitis. A discussion of differential diagnosis is also presented.
AB - Evaluation of needle biopsies and extensive clinicopathological correlation play an important role in the determination of liver allograft dysfunction occurring more than 1 year after transplantation. Interpretation of these biopsies can be quite difficult because of the high incidence of recurrent diseases that show histopathological, clinical, and serological features that overlap with each other and with rejection. Also, more than one insult can contribute to allograft injury. In an attempt to enable centers to compare and pool results, improve therapy, and better understand pathophysiological disease mechanisms, the Banff Working Group on Liver Allograft Pathology herein proposes a set of consensus criteria for the most common and problematic causes of late liver allograft dysfunction, including late-onset acute and chronic rejection, recurrent and new-onset viral and autoimmune hepatitis, biliary strictures, and recurrent primary biliary cirrhosis and primary sclerosing cholangitis. A discussion of differential diagnosis is also presented.
UR - http://www.scopus.com/inward/record.url?scp=33747080802&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33747080802&partnerID=8YFLogxK
U2 - 10.1002/hep.21280
DO - 10.1002/hep.21280
M3 - Review article
C2 - 16871565
VL - 44
SP - 489
EP - 501
JO - Hepatology
JF - Hepatology
SN - 0270-9139
IS - 2
ER -