Linkage between Rh blood group and autosomal dominant retinitis pigmentosa in ten Chinese families.

Y. J. Fei, S. H. Blanton, S. P. Daiger, C. R. Luo

Research output: Contribution to journalArticle

Abstract

Since Fei et al reported a tentative linkage between ADRP and the Rhesus(Rh) blood group in the unrelated Chinese families in 1987, additional individuals of these ADRP families have been typed for Rh. Further linkage analysis with the LIPED Program on the Rh data of the ten ADRP families showed a maximum summed LOD score of 2.01 at theta = 0.12, which is a further suggestion of linkage between ADRP and Rh. However, genetic heterogeneity certainly exists in these families. It is our presumption that ADRP in those families, which do not exhibit linkage to 3q markers, may map to the short arm of chromosome 1.

Original languageEnglish (US)
Pages (from-to)486-489
Number of pages4
JournalChinese medical journal
Volume105
Issue number6
StatePublished - Jun 1992
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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