Linkage analysis in familial Alzheimer disease

Description of the Duke and Boston data sets

Margaret A Pericak-Vance, P. H. St. George-Hyslop, P. C. Gaskell, J. Growdon, B. J. Crain, C. Hulette, J. F. Gusella, L. Yamaoka, R. E. Tanzi, A. D. Roses, J. L. Haines

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Familial Alzheimer disease is a neurological disorder of adult onset. Three research centers have each contributed their families and genetic linkage data for combined analyses. The data from the Duke and Boston centers, comprising 73 pedigrees for whom numerous markers on chromosomes 19 and 21 were typed, are described.

Original languageEnglish
Pages (from-to)361-364
Number of pages4
JournalGenetic Epidemiology
Volume10
Issue number6
DOIs
StatePublished - Dec 1 1993
Externally publishedYes

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Chromosomes, Human, Pair 19
Chromosomes, Human, Pair 21
Genetic Linkage
Pedigree
Nervous System Diseases
Alzheimer Disease
Research
Datasets

ASJC Scopus subject areas

  • Genetics(clinical)
  • Epidemiology

Cite this

Pericak-Vance, M. A., St. George-Hyslop, P. H., Gaskell, P. C., Growdon, J., Crain, B. J., Hulette, C., ... Haines, J. L. (1993). Linkage analysis in familial Alzheimer disease: Description of the Duke and Boston data sets. Genetic Epidemiology, 10(6), 361-364. https://doi.org/10.1002/gepi.1370100605

Linkage analysis in familial Alzheimer disease : Description of the Duke and Boston data sets. / Pericak-Vance, Margaret A; St. George-Hyslop, P. H.; Gaskell, P. C.; Growdon, J.; Crain, B. J.; Hulette, C.; Gusella, J. F.; Yamaoka, L.; Tanzi, R. E.; Roses, A. D.; Haines, J. L.

In: Genetic Epidemiology, Vol. 10, No. 6, 01.12.1993, p. 361-364.

Research output: Contribution to journalArticle

Pericak-Vance, MA, St. George-Hyslop, PH, Gaskell, PC, Growdon, J, Crain, BJ, Hulette, C, Gusella, JF, Yamaoka, L, Tanzi, RE, Roses, AD & Haines, JL 1993, 'Linkage analysis in familial Alzheimer disease: Description of the Duke and Boston data sets', Genetic Epidemiology, vol. 10, no. 6, pp. 361-364. https://doi.org/10.1002/gepi.1370100605
Pericak-Vance, Margaret A ; St. George-Hyslop, P. H. ; Gaskell, P. C. ; Growdon, J. ; Crain, B. J. ; Hulette, C. ; Gusella, J. F. ; Yamaoka, L. ; Tanzi, R. E. ; Roses, A. D. ; Haines, J. L. / Linkage analysis in familial Alzheimer disease : Description of the Duke and Boston data sets. In: Genetic Epidemiology. 1993 ; Vol. 10, No. 6. pp. 361-364.
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