Linkage analysis in familial Alzheimer disease: Description of the Duke and Boston data sets

M. A. Pericak‐Vance, P. H. St. George‐Hyslop, P. C. Gaskell, J. Growdon, B. J. Crain, C. Hulette, J. F. Gusella, L. Yamaoka, R. E. Tanzi, A. D. Roses, J. L. Haines

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6 Scopus citations

Abstract

Familial Alzheimer disease is a neurological disorder of adult onset. Three research centers have each contributed their families and genetic linkage data for combined analyses. The data from the Duke and Boston centers, comprising 73 pedigrees for whom numerous markers on chromosomes 19 and 21 were typed, are described.

Original languageEnglish (US)
Pages (from-to)361-364
Number of pages4
JournalGenetic Epidemiology
Volume10
Issue number6
DOIs
StatePublished - 1993

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Keywords

  • FAD
  • familial Alzheimer disease
  • families
  • linkage

ASJC Scopus subject areas

  • Epidemiology
  • Genetics(clinical)

Cite this

Pericak‐Vance, M. A., St. George‐Hyslop, P. H., Gaskell, P. C., Growdon, J., Crain, B. J., Hulette, C., Gusella, J. F., Yamaoka, L., Tanzi, R. E., Roses, A. D., & Haines, J. L. (1993). Linkage analysis in familial Alzheimer disease: Description of the Duke and Boston data sets. Genetic Epidemiology, 10(6), 361-364. https://doi.org/10.1002/gepi.1370100605