Lineshape estimation in in vivo MR spectroscopy without using a reference signal

E. Popa, D. Graveron-Demilly, E. Capobianco, R. De Beer, D. Van Ormondt

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Scopus citations

Abstract

Metabolites can serve as biomarkers. Estimation of metabolite concentrations from an in vivo MRS signal often uses a reference signal from water for correction of the spectral lineshape. When no reference signal is available, other methods must be applied. The present work concerns semi-parametric estimation of the perturbed line-shape from simulated signals of the metabolites themselves. Errors are obtained from a Monte-Carlo calculation. The method can be useful when the water signal has not been acquired or is distorted, or when measuring on, e.g., 13C or 31P.

Original languageEnglish (US)
Title of host publicationIST 2008 - IEEE Workshop on Imaging Systems and Techniques Proceedings
Pages315-320
Number of pages6
DOIs
StatePublished - 2008
Externally publishedYes
EventIEEE Workshop on Imaging Systems and Techniques, IST 2008 - Chania, Crete, Greece
Duration: Sep 10 2008Sep 12 2008

Publication series

NameIST 2008 - IEEE Workshop on Imaging Systems and Techniques Proceedings

Conference

ConferenceIEEE Workshop on Imaging Systems and Techniques, IST 2008
Country/TerritoryGreece
CityChania, Crete
Period9/10/089/12/08

Keywords

  • Asymmetric lineshape
  • Estimation error
  • In vivo
  • Metabolomics
  • MR spectroscopy
  • Simulations

ASJC Scopus subject areas

  • Computer Vision and Pattern Recognition
  • Control and Systems Engineering
  • Electrical and Electronic Engineering

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