Line scan proton spin imaging in biological structures by NMR

P. Mansfield, A. A. Maudsley

Research output: Contribution to journalArticlepeer-review

51 Scopus citations

Abstract

The proton scan images produced in this note represent static distributions of the free water (fat or oil) contained in the various biological specimens. The times taken to produce these pictures range from 7.0 to 60 min. The times were chosen to accentuate T1 effects, particularly in the plant specimens, and are not limits intrinsic to the mapping method. If the water distribution is changing relatively slowly, as in diffusion in plants, for example, it should be possible to study such variations in vivo. Most of the NMR pictures we have produced do in fact bear a resemblance to the visual cross section of the specimen. However, since our pictures represent distributions of water (or free proton) concentration, these will not always coincide with the physical shape as seen by eye. The comparison is rather like looking at a photograph of a man and comparing it with his X-ray picture. With these differences in mind, the interpretation of proton scans, particularly when taken together with T1 mapping, have to be treated with care. Nevertheless, it is believed that NMR imaging will be a valuable medical diagnostic aid in man as well as a useful tool for the biologist and botanist.

Original languageEnglish (US)
Article number013
Pages (from-to)847-852
Number of pages6
JournalPhysics in Medicine and Biology
Volume21
Issue number5
DOIs
StatePublished - Dec 1 1976
Externally publishedYes

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging

Fingerprint Dive into the research topics of 'Line scan proton spin imaging in biological structures by NMR'. Together they form a unique fingerprint.

Cite this