Limited macular translocation: A clinicopathologic case report

Thomas A Albini, Narsing A. Rao, Aimin Li, Cheryl M. Craft, Gildo Y. Fujii, Eugene De Juan

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Objective To illustrate the histopathologic findings in a patient who underwent limited macular translocation. Design Observational case report. Methods The patient underwent limited macular translocation for subfoveal choroidal neovascularization resulting from age-related macular degeneration. Thirty-one months after surgery, the patient had died and both eyes were obtained at autopsy. Serial sections through both maculas were obtained. Immunohistochemistry of the foveas with C10C10 and hCAR/LUMIf antibodies for rods and cones, respectively, was performed. Main outcome measures Histopathologic changes in the operated eye as compared with the fellow eye. Results There was no morphologic difference in the subfoveal retinal pigment epithelium, Bruch's membrane, or choriocapillaris, but there was a decreased cone density in the translocated fovea as compared with the fellow eye. Conclusions In this patient, the fovea was translocated without causing apparent change in the underlying retinal pigment epithelium, Bruch's membrane, or choriocapillaris. Although there may be some photoreceptor loss, the excellent visual recovery suggests that the retinal pigment epithelium underlying the translocated fovea is functionally adequate.

Original languageEnglish
Pages (from-to)1209-1214
Number of pages6
JournalOphthalmology
Volume111
Issue number6
DOIs
StatePublished - Jun 1 2004
Externally publishedYes

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Retinal Pigment Epithelium
Bruch Membrane
Choroidal Neovascularization
Vertebrate Photoreceptor Cells
Macular Degeneration
Autopsy
Immunohistochemistry
Outcome Assessment (Health Care)
Antibodies

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Albini, T. A., Rao, N. A., Li, A., Craft, C. M., Fujii, G. Y., & De Juan, E. (2004). Limited macular translocation: A clinicopathologic case report. Ophthalmology, 111(6), 1209-1214. https://doi.org/10.1016/j.ophtha.2003.10.021

Limited macular translocation : A clinicopathologic case report. / Albini, Thomas A; Rao, Narsing A.; Li, Aimin; Craft, Cheryl M.; Fujii, Gildo Y.; De Juan, Eugene.

In: Ophthalmology, Vol. 111, No. 6, 01.06.2004, p. 1209-1214.

Research output: Contribution to journalArticle

Albini, TA, Rao, NA, Li, A, Craft, CM, Fujii, GY & De Juan, E 2004, 'Limited macular translocation: A clinicopathologic case report', Ophthalmology, vol. 111, no. 6, pp. 1209-1214. https://doi.org/10.1016/j.ophtha.2003.10.021
Albini, Thomas A ; Rao, Narsing A. ; Li, Aimin ; Craft, Cheryl M. ; Fujii, Gildo Y. ; De Juan, Eugene. / Limited macular translocation : A clinicopathologic case report. In: Ophthalmology. 2004 ; Vol. 111, No. 6. pp. 1209-1214.
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