Limitations of diazoxide reversal of vasospasm

Roberto C. Heros, Michael H. Lavyne

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Diazoxide failed to safely relieve cerebral vasospasm by intracisternal injections in dogs and by intracarotid injections in monkeys despite in vitro documentation of arterial relaxation with this agent. Administration of the drug frequently produced hypertension and, in the presence of vasospasm, was associated with a high mortality rate.

Original languageEnglish (US)
Pages (from-to)118-120
Number of pages3
Issue number2
StatePublished - 1976
Externally publishedYes

ASJC Scopus subject areas

  • Clinical Neurology
  • Cardiology and Cardiovascular Medicine
  • Advanced and Specialized Nursing


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