Limitations of diazoxide reversal of vasospasm

Roberto C. Heros, Michael H. Lavyne

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

Diazoxide failed to safely relieve cerebral vasospasm by intracisternal injections in dogs and by intracarotid injections in monkeys despite in vitro documentation of arterial relaxation with this agent. Administration of the drug frequently produced hypertension and, in the presence of vasospasm, was associated with a high mortality rate.

Original languageEnglish (US)
Pages (from-to)118-120
Number of pages3
JournalStroke
Volume7
Issue number2
DOIs
StatePublished - Jan 1 1976
Externally publishedYes

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ASJC Scopus subject areas

  • Clinical Neurology
  • Cardiology and Cardiovascular Medicine
  • Advanced and Specialized Nursing

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