Limb salvage with osteoarticular allografts after resection of proximal tibia bone tumors

F. J. Hornicek, W. Mnaymneh, R. D. Lackman, G. U. Exner, Theodore Malinin

Research output: Contribution to journalArticle

78 Citations (Scopus)

Abstract

A retrospective study was performed between 1980 and 1995 on 38 recipients of proximal tibial allografts after wide resection of benign and malignant tumors. Twenty-one (55%) patients experienced one or more complications. Of the 26 patients who received chemotherapy, 15 (58%) experienced one or more complications, whereas of the 12 patients who did not receive chemotherapy, six (50%) experienced one or more complications. In the chemotherapy group, there were 12 (46%) fractures, four (15%) infections, three (12%) nonunions, and four (15%) instabilities. In the nonchemotherapy group there were three (25%) infections, two (17%) fractures, one (8%) instability, and one (8%) nonunion. These complications were managed adequately with multiple subsequent surgical procedures. Three patients underwent amputations for deep wound infections. Twelve (32%) patients underwent removal of the allograft, and the limb was salvaged by reallografting or by total knee arthroplasty. The results of both groups were 66% (25 of 38 patients) satisfactory (good or excellent). The chemotherapy group had a significantly higher incidence of fractures. All other complication rates and functional outcomes were not significantly different between these groups.

Original languageEnglish
Pages (from-to)179-186
Number of pages8
JournalClinical Orthopaedics and Related Research
Issue number352
StatePublished - Jul 24 1998

Fingerprint

Limb Salvage
Tibia
Allografts
Bone and Bones
Drug Therapy
Neoplasms
Knee Replacement Arthroplasties
Wound Infection
Infection
Amputation
Extremities
Retrospective Studies
Incidence

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine

Cite this

Hornicek, F. J., Mnaymneh, W., Lackman, R. D., Exner, G. U., & Malinin, T. (1998). Limb salvage with osteoarticular allografts after resection of proximal tibia bone tumors. Clinical Orthopaedics and Related Research, (352), 179-186.

Limb salvage with osteoarticular allografts after resection of proximal tibia bone tumors. / Hornicek, F. J.; Mnaymneh, W.; Lackman, R. D.; Exner, G. U.; Malinin, Theodore.

In: Clinical Orthopaedics and Related Research, No. 352, 24.07.1998, p. 179-186.

Research output: Contribution to journalArticle

Hornicek, FJ, Mnaymneh, W, Lackman, RD, Exner, GU & Malinin, T 1998, 'Limb salvage with osteoarticular allografts after resection of proximal tibia bone tumors', Clinical Orthopaedics and Related Research, no. 352, pp. 179-186.
Hornicek FJ, Mnaymneh W, Lackman RD, Exner GU, Malinin T. Limb salvage with osteoarticular allografts after resection of proximal tibia bone tumors. Clinical Orthopaedics and Related Research. 1998 Jul 24;(352):179-186.
Hornicek, F. J. ; Mnaymneh, W. ; Lackman, R. D. ; Exner, G. U. ; Malinin, Theodore. / Limb salvage with osteoarticular allografts after resection of proximal tibia bone tumors. In: Clinical Orthopaedics and Related Research. 1998 ; No. 352. pp. 179-186.
@article{d53927eb69154660acd3986996d5fe23,
title = "Limb salvage with osteoarticular allografts after resection of proximal tibia bone tumors",
abstract = "A retrospective study was performed between 1980 and 1995 on 38 recipients of proximal tibial allografts after wide resection of benign and malignant tumors. Twenty-one (55{\%}) patients experienced one or more complications. Of the 26 patients who received chemotherapy, 15 (58{\%}) experienced one or more complications, whereas of the 12 patients who did not receive chemotherapy, six (50{\%}) experienced one or more complications. In the chemotherapy group, there were 12 (46{\%}) fractures, four (15{\%}) infections, three (12{\%}) nonunions, and four (15{\%}) instabilities. In the nonchemotherapy group there were three (25{\%}) infections, two (17{\%}) fractures, one (8{\%}) instability, and one (8{\%}) nonunion. These complications were managed adequately with multiple subsequent surgical procedures. Three patients underwent amputations for deep wound infections. Twelve (32{\%}) patients underwent removal of the allograft, and the limb was salvaged by reallografting or by total knee arthroplasty. The results of both groups were 66{\%} (25 of 38 patients) satisfactory (good or excellent). The chemotherapy group had a significantly higher incidence of fractures. All other complication rates and functional outcomes were not significantly different between these groups.",
author = "Hornicek, {F. J.} and W. Mnaymneh and Lackman, {R. D.} and Exner, {G. U.} and Theodore Malinin",
year = "1998",
month = "7",
day = "24",
language = "English",
pages = "179--186",
journal = "Clinical Orthopaedics and Related Research",
issn = "0009-921X",
publisher = "Springer New York",
number = "352",

}

TY - JOUR

T1 - Limb salvage with osteoarticular allografts after resection of proximal tibia bone tumors

AU - Hornicek, F. J.

AU - Mnaymneh, W.

AU - Lackman, R. D.

AU - Exner, G. U.

AU - Malinin, Theodore

PY - 1998/7/24

Y1 - 1998/7/24

N2 - A retrospective study was performed between 1980 and 1995 on 38 recipients of proximal tibial allografts after wide resection of benign and malignant tumors. Twenty-one (55%) patients experienced one or more complications. Of the 26 patients who received chemotherapy, 15 (58%) experienced one or more complications, whereas of the 12 patients who did not receive chemotherapy, six (50%) experienced one or more complications. In the chemotherapy group, there were 12 (46%) fractures, four (15%) infections, three (12%) nonunions, and four (15%) instabilities. In the nonchemotherapy group there were three (25%) infections, two (17%) fractures, one (8%) instability, and one (8%) nonunion. These complications were managed adequately with multiple subsequent surgical procedures. Three patients underwent amputations for deep wound infections. Twelve (32%) patients underwent removal of the allograft, and the limb was salvaged by reallografting or by total knee arthroplasty. The results of both groups were 66% (25 of 38 patients) satisfactory (good or excellent). The chemotherapy group had a significantly higher incidence of fractures. All other complication rates and functional outcomes were not significantly different between these groups.

AB - A retrospective study was performed between 1980 and 1995 on 38 recipients of proximal tibial allografts after wide resection of benign and malignant tumors. Twenty-one (55%) patients experienced one or more complications. Of the 26 patients who received chemotherapy, 15 (58%) experienced one or more complications, whereas of the 12 patients who did not receive chemotherapy, six (50%) experienced one or more complications. In the chemotherapy group, there were 12 (46%) fractures, four (15%) infections, three (12%) nonunions, and four (15%) instabilities. In the nonchemotherapy group there were three (25%) infections, two (17%) fractures, one (8%) instability, and one (8%) nonunion. These complications were managed adequately with multiple subsequent surgical procedures. Three patients underwent amputations for deep wound infections. Twelve (32%) patients underwent removal of the allograft, and the limb was salvaged by reallografting or by total knee arthroplasty. The results of both groups were 66% (25 of 38 patients) satisfactory (good or excellent). The chemotherapy group had a significantly higher incidence of fractures. All other complication rates and functional outcomes were not significantly different between these groups.

UR - http://www.scopus.com/inward/record.url?scp=0345310057&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0345310057&partnerID=8YFLogxK

M3 - Article

C2 - 9678046

AN - SCOPUS:0345310057

SP - 179

EP - 186

JO - Clinical Orthopaedics and Related Research

JF - Clinical Orthopaedics and Related Research

SN - 0009-921X

IS - 352

ER -