Lifestyle modification and weight reduction among low-income patients with the metabolic syndrome: the CHARMS randomized controlled trial

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6 Scopus citations

Abstract

Although weight is an important intervention target among patients with metabolic syndrome, few trials have recruited low-income minority populations. The Community Health and Risk-reduction for Metabolic Syndrome randomized controlled trial aimed to examine the effects of a lifestyle intervention on weight and metabolic syndrome components among low-income minority adults. We randomized 120 adults with metabolic syndrome to standard medical care (N = 60) or a lifestyle intervention (N = 60). Using an intent-to-treat approach, we found significant intervention effects on weight [B = −0.452; SE = 0.122; 95 % confidence intervals (CI) −0.653 to −0.251) and glucose levels at 6-months (B = −0.522, SE = 0.234, 95 % CI −0.907 to −0.138). These changes were maintained through the 12-month assessment. No significant effects were observed on insulin resistance or other metabolic syndrome components. Our intervention was successful in achieving modest but significant weight loss and reduction in fasting glucose among low-income minority subjects with metabolic syndrome.

Original languageEnglish (US)
Pages (from-to)483-492
Number of pages10
JournalJournal of Behavioral Medicine
Volume39
Issue number3
DOIs
StatePublished - Jun 1 2016

Keywords

  • Cardiovascular disease
  • Hispanics
  • Intervention
  • Metabolic syndrome
  • Minority populations
  • Randomized controlled trial
  • Weight

ASJC Scopus subject areas

  • Psychology(all)
  • Psychiatry and Mental health

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