Lifestyle modification and weight reduction among low-income patients with the metabolic syndrome: the CHARMS randomized controlled trial

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6 Citations (Scopus)

Abstract

Although weight is an important intervention target among patients with metabolic syndrome, few trials have recruited low-income minority populations. The Community Health and Risk-reduction for Metabolic Syndrome randomized controlled trial aimed to examine the effects of a lifestyle intervention on weight and metabolic syndrome components among low-income minority adults. We randomized 120 adults with metabolic syndrome to standard medical care (N = 60) or a lifestyle intervention (N = 60). Using an intent-to-treat approach, we found significant intervention effects on weight [B = −0.452; SE = 0.122; 95 % confidence intervals (CI) −0.653 to −0.251) and glucose levels at 6-months (B = −0.522, SE = 0.234, 95 % CI −0.907 to −0.138). These changes were maintained through the 12-month assessment. No significant effects were observed on insulin resistance or other metabolic syndrome components. Our intervention was successful in achieving modest but significant weight loss and reduction in fasting glucose among low-income minority subjects with metabolic syndrome.

Original languageEnglish (US)
Pages (from-to)1-10
Number of pages10
JournalJournal of Behavioral Medicine
DOIs
StateAccepted/In press - Feb 4 2016

Fingerprint

Life Style
Weight Loss
Randomized Controlled Trials
Weights and Measures
Confidence Intervals
Glucose
Risk Reduction Behavior
Poverty
Insulin Resistance
Fasting
Health

Keywords

  • Cardiovascular disease
  • Hispanics
  • Intervention
  • Metabolic syndrome
  • Minority populations
  • Randomized controlled trial
  • Weight

ASJC Scopus subject areas

  • Psychology(all)
  • Psychiatry and Mental health

Cite this

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title = "Lifestyle modification and weight reduction among low-income patients with the metabolic syndrome: the CHARMS randomized controlled trial",
abstract = "Although weight is an important intervention target among patients with metabolic syndrome, few trials have recruited low-income minority populations. The Community Health and Risk-reduction for Metabolic Syndrome randomized controlled trial aimed to examine the effects of a lifestyle intervention on weight and metabolic syndrome components among low-income minority adults. We randomized 120 adults with metabolic syndrome to standard medical care (N = 60) or a lifestyle intervention (N = 60). Using an intent-to-treat approach, we found significant intervention effects on weight [B = −0.452; SE = 0.122; 95 {\%} confidence intervals (CI) −0.653 to −0.251) and glucose levels at 6-months (B = −0.522, SE = 0.234, 95 {\%} CI −0.907 to −0.138). These changes were maintained through the 12-month assessment. No significant effects were observed on insulin resistance or other metabolic syndrome components. Our intervention was successful in achieving modest but significant weight loss and reduction in fasting glucose among low-income minority subjects with metabolic syndrome.",
keywords = "Cardiovascular disease, Hispanics, Intervention, Metabolic syndrome, Minority populations, Randomized controlled trial, Weight",
author = "Chirinos, {Diana A.} and Goldberg, {Ronald B} and Maria Llabre and Marc Gellman and Miriam Gutt and Judith McCalla and Mendez, {Armando J} and Neil Schneiderman",
year = "2016",
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T2 - the CHARMS randomized controlled trial

AU - Chirinos, Diana A.

AU - Goldberg, Ronald B

AU - Llabre, Maria

AU - Gellman, Marc

AU - Gutt, Miriam

AU - McCalla, Judith

AU - Mendez, Armando J

AU - Schneiderman, Neil

PY - 2016/2/4

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N2 - Although weight is an important intervention target among patients with metabolic syndrome, few trials have recruited low-income minority populations. The Community Health and Risk-reduction for Metabolic Syndrome randomized controlled trial aimed to examine the effects of a lifestyle intervention on weight and metabolic syndrome components among low-income minority adults. We randomized 120 adults with metabolic syndrome to standard medical care (N = 60) or a lifestyle intervention (N = 60). Using an intent-to-treat approach, we found significant intervention effects on weight [B = −0.452; SE = 0.122; 95 % confidence intervals (CI) −0.653 to −0.251) and glucose levels at 6-months (B = −0.522, SE = 0.234, 95 % CI −0.907 to −0.138). These changes were maintained through the 12-month assessment. No significant effects were observed on insulin resistance or other metabolic syndrome components. Our intervention was successful in achieving modest but significant weight loss and reduction in fasting glucose among low-income minority subjects with metabolic syndrome.

AB - Although weight is an important intervention target among patients with metabolic syndrome, few trials have recruited low-income minority populations. The Community Health and Risk-reduction for Metabolic Syndrome randomized controlled trial aimed to examine the effects of a lifestyle intervention on weight and metabolic syndrome components among low-income minority adults. We randomized 120 adults with metabolic syndrome to standard medical care (N = 60) or a lifestyle intervention (N = 60). Using an intent-to-treat approach, we found significant intervention effects on weight [B = −0.452; SE = 0.122; 95 % confidence intervals (CI) −0.653 to −0.251) and glucose levels at 6-months (B = −0.522, SE = 0.234, 95 % CI −0.907 to −0.138). These changes were maintained through the 12-month assessment. No significant effects were observed on insulin resistance or other metabolic syndrome components. Our intervention was successful in achieving modest but significant weight loss and reduction in fasting glucose among low-income minority subjects with metabolic syndrome.

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KW - Minority populations

KW - Randomized controlled trial

KW - Weight

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