Life-threatening hyperkalemia in severe heart failure

Simon C. Chakko, John Frutchey, Mihai Gheorghiade

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

The therapeutic course of patients with severe heart failure can be complicated by disturbances in potassium homeostasis. Although hypokalemia in more prevalent, hyperkalemia may occur. Among 730 consecutive patients admitted to the hospital because of heart failure, nine episodes of acute, life-threatening hyperkalemia (mean serum potassium level: 7.2 ± 0.5 mEq/L) were diagnosed in six patients (0.8%) with severe chronic heart failure during maintenance oral potassium therapy and exacerbation of heart failure and/or after additional oral doses had been administered for correction of hypokalemia. Of nine hyperkalemic episodes observed, one was fatal, seven episodes were successfully treated, and one resolved spontaneously. Only one patient was receiving and angiotensin-converting enzyme inhibitor. An awareness of this complication and the clinical setting in which it is likely to occur could lead to earlier recognition and successful management.

Original languageEnglish
Pages (from-to)1083-1091
Number of pages9
JournalAmerican Heart Journal
Volume117
Issue number5
DOIs
StatePublished - Jan 1 1989
Externally publishedYes

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Hyperkalemia
Heart Failure
Potassium
Hypokalemia
Angiotensin-Converting Enzyme Inhibitors
Homeostasis
Maintenance
Therapeutics
Serum

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Life-threatening hyperkalemia in severe heart failure. / Chakko, Simon C.; Frutchey, John; Gheorghiade, Mihai.

In: American Heart Journal, Vol. 117, No. 5, 01.01.1989, p. 1083-1091.

Research output: Contribution to journalArticle

Chakko, SC, Frutchey, J & Gheorghiade, M 1989, 'Life-threatening hyperkalemia in severe heart failure', American Heart Journal, vol. 117, no. 5, pp. 1083-1091. https://doi.org/10.1016/0002-8703(89)90866-1
Chakko, Simon C. ; Frutchey, John ; Gheorghiade, Mihai. / Life-threatening hyperkalemia in severe heart failure. In: American Heart Journal. 1989 ; Vol. 117, No. 5. pp. 1083-1091.
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