Life impairments in adults with medication-treated ADHD

Steven Safren, Susan E. Sprich, Christine Cooper-Vince, Laura E. Knouse, Jonathan A. Lerner

Research output: Contribution to journalArticle

42 Citations (Scopus)

Abstract

Objective: In developing psychosocial approaches to augment outcomes for medication-treated adults with ADHD, it is important to understand what types of life-impairments are most affected by continued ADHD symptoms that occur despite medication treatment. This may assist in delineating targets for interventions, as well as assessments of functional outcomes that are sensitive to change in this population. Method: The sample consists of 105 adults with ADHD presenting for entry into clinical trials of CBT for residual ADHD. Life impairments are rated by a clinician using the LIFE-RIFT, which has subscales for work impairment, interpersonal impairment, life-satisfaction, and recreation, ADHD symptoms using the ADHD Rating Scale, overall ADHD severity using the clinical global impression, and associated distress using the Hamilton Depression and Anxiety Rating Scales. Results: The most problematic impairments are in the domain of work, followed by interpersonal. Generally, the subscales of the LIFE-RIFT are associated, at the bivariate level, with all 4 symptom indices. Work and interpersonal impairments are uniquely associated with overall severity of ADHD symptoms using both the CGI and the ADHD Rating Scale. However interpersonal and life-satisfaction impairments are uniquely associated with depression, and life-satisfaction is uniquely associated with anxiety. Conclusion: In medication-treated adults with ADHD, work and interpersonal impairments appear to be the most problematic areas of life-impairment, which are uniquely associated with ADHD severity. Life-satisfaction appears to be uniquely associated with distress as defined by anxiety and depression symptoms, with interpersonal impairments also playing a role. Psychosocial treatments for medication treated adults should target work and interpersonal domains and should include skills for managing associated distress.

Original languageEnglish (US)
Pages (from-to)524-531
Number of pages8
JournalJournal of Attention Disorders
Volume13
Issue number5
DOIs
StatePublished - Mar 2010
Externally publishedYes

Fingerprint

Anxiety
Depression
Recreation
Outcome Assessment (Health Care)
Clinical Trials
Population

Keywords

  • Adults
  • Life impairments
  • Life satisfaction
  • Quality of life

ASJC Scopus subject areas

  • Clinical Psychology
  • Developmental and Educational Psychology

Cite this

Safren, S., Sprich, S. E., Cooper-Vince, C., Knouse, L. E., & Lerner, J. A. (2010). Life impairments in adults with medication-treated ADHD. Journal of Attention Disorders, 13(5), 524-531. https://doi.org/10.1177/1087054709332460

Life impairments in adults with medication-treated ADHD. / Safren, Steven; Sprich, Susan E.; Cooper-Vince, Christine; Knouse, Laura E.; Lerner, Jonathan A.

In: Journal of Attention Disorders, Vol. 13, No. 5, 03.2010, p. 524-531.

Research output: Contribution to journalArticle

Safren, S, Sprich, SE, Cooper-Vince, C, Knouse, LE & Lerner, JA 2010, 'Life impairments in adults with medication-treated ADHD', Journal of Attention Disorders, vol. 13, no. 5, pp. 524-531. https://doi.org/10.1177/1087054709332460
Safren, Steven ; Sprich, Susan E. ; Cooper-Vince, Christine ; Knouse, Laura E. ; Lerner, Jonathan A. / Life impairments in adults with medication-treated ADHD. In: Journal of Attention Disorders. 2010 ; Vol. 13, No. 5. pp. 524-531.
@article{34919c6dc3eb43998b3234f7779396b7,
title = "Life impairments in adults with medication-treated ADHD",
abstract = "Objective: In developing psychosocial approaches to augment outcomes for medication-treated adults with ADHD, it is important to understand what types of life-impairments are most affected by continued ADHD symptoms that occur despite medication treatment. This may assist in delineating targets for interventions, as well as assessments of functional outcomes that are sensitive to change in this population. Method: The sample consists of 105 adults with ADHD presenting for entry into clinical trials of CBT for residual ADHD. Life impairments are rated by a clinician using the LIFE-RIFT, which has subscales for work impairment, interpersonal impairment, life-satisfaction, and recreation, ADHD symptoms using the ADHD Rating Scale, overall ADHD severity using the clinical global impression, and associated distress using the Hamilton Depression and Anxiety Rating Scales. Results: The most problematic impairments are in the domain of work, followed by interpersonal. Generally, the subscales of the LIFE-RIFT are associated, at the bivariate level, with all 4 symptom indices. Work and interpersonal impairments are uniquely associated with overall severity of ADHD symptoms using both the CGI and the ADHD Rating Scale. However interpersonal and life-satisfaction impairments are uniquely associated with depression, and life-satisfaction is uniquely associated with anxiety. Conclusion: In medication-treated adults with ADHD, work and interpersonal impairments appear to be the most problematic areas of life-impairment, which are uniquely associated with ADHD severity. Life-satisfaction appears to be uniquely associated with distress as defined by anxiety and depression symptoms, with interpersonal impairments also playing a role. Psychosocial treatments for medication treated adults should target work and interpersonal domains and should include skills for managing associated distress.",
keywords = "Adults, Life impairments, Life satisfaction, Quality of life",
author = "Steven Safren and Sprich, {Susan E.} and Christine Cooper-Vince and Knouse, {Laura E.} and Lerner, {Jonathan A.}",
year = "2010",
month = "3",
doi = "10.1177/1087054709332460",
language = "English (US)",
volume = "13",
pages = "524--531",
journal = "Journal of Attention Disorders",
issn = "1087-0547",
publisher = "SAGE Publications Inc.",
number = "5",

}

TY - JOUR

T1 - Life impairments in adults with medication-treated ADHD

AU - Safren, Steven

AU - Sprich, Susan E.

AU - Cooper-Vince, Christine

AU - Knouse, Laura E.

AU - Lerner, Jonathan A.

PY - 2010/3

Y1 - 2010/3

N2 - Objective: In developing psychosocial approaches to augment outcomes for medication-treated adults with ADHD, it is important to understand what types of life-impairments are most affected by continued ADHD symptoms that occur despite medication treatment. This may assist in delineating targets for interventions, as well as assessments of functional outcomes that are sensitive to change in this population. Method: The sample consists of 105 adults with ADHD presenting for entry into clinical trials of CBT for residual ADHD. Life impairments are rated by a clinician using the LIFE-RIFT, which has subscales for work impairment, interpersonal impairment, life-satisfaction, and recreation, ADHD symptoms using the ADHD Rating Scale, overall ADHD severity using the clinical global impression, and associated distress using the Hamilton Depression and Anxiety Rating Scales. Results: The most problematic impairments are in the domain of work, followed by interpersonal. Generally, the subscales of the LIFE-RIFT are associated, at the bivariate level, with all 4 symptom indices. Work and interpersonal impairments are uniquely associated with overall severity of ADHD symptoms using both the CGI and the ADHD Rating Scale. However interpersonal and life-satisfaction impairments are uniquely associated with depression, and life-satisfaction is uniquely associated with anxiety. Conclusion: In medication-treated adults with ADHD, work and interpersonal impairments appear to be the most problematic areas of life-impairment, which are uniquely associated with ADHD severity. Life-satisfaction appears to be uniquely associated with distress as defined by anxiety and depression symptoms, with interpersonal impairments also playing a role. Psychosocial treatments for medication treated adults should target work and interpersonal domains and should include skills for managing associated distress.

AB - Objective: In developing psychosocial approaches to augment outcomes for medication-treated adults with ADHD, it is important to understand what types of life-impairments are most affected by continued ADHD symptoms that occur despite medication treatment. This may assist in delineating targets for interventions, as well as assessments of functional outcomes that are sensitive to change in this population. Method: The sample consists of 105 adults with ADHD presenting for entry into clinical trials of CBT for residual ADHD. Life impairments are rated by a clinician using the LIFE-RIFT, which has subscales for work impairment, interpersonal impairment, life-satisfaction, and recreation, ADHD symptoms using the ADHD Rating Scale, overall ADHD severity using the clinical global impression, and associated distress using the Hamilton Depression and Anxiety Rating Scales. Results: The most problematic impairments are in the domain of work, followed by interpersonal. Generally, the subscales of the LIFE-RIFT are associated, at the bivariate level, with all 4 symptom indices. Work and interpersonal impairments are uniquely associated with overall severity of ADHD symptoms using both the CGI and the ADHD Rating Scale. However interpersonal and life-satisfaction impairments are uniquely associated with depression, and life-satisfaction is uniquely associated with anxiety. Conclusion: In medication-treated adults with ADHD, work and interpersonal impairments appear to be the most problematic areas of life-impairment, which are uniquely associated with ADHD severity. Life-satisfaction appears to be uniquely associated with distress as defined by anxiety and depression symptoms, with interpersonal impairments also playing a role. Psychosocial treatments for medication treated adults should target work and interpersonal domains and should include skills for managing associated distress.

KW - Adults

KW - Life impairments

KW - Life satisfaction

KW - Quality of life

UR - http://www.scopus.com/inward/record.url?scp=77649256415&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77649256415&partnerID=8YFLogxK

U2 - 10.1177/1087054709332460

DO - 10.1177/1087054709332460

M3 - Article

C2 - 19395647

AN - SCOPUS:77649256415

VL - 13

SP - 524

EP - 531

JO - Journal of Attention Disorders

JF - Journal of Attention Disorders

SN - 1087-0547

IS - 5

ER -