LH-RH agonists and antagonists

Andrew V Schally, D. H. Coy, A. Arimura

Research output: Contribution to journalArticle

63 Citations (Scopus)

Abstract

Large doses of stimulatory analogues of luteinizing hormone-releasing hormone (LH-RH) caused paradoxical antifertility effects. These effects are being utilized for the possible development of contraceptive methods. Several inhibitory analogues of LH-RH have been tested in men and women and shown to be active. The synthetic approach based on inhibitory analogues of LH-RH has been proven to be feasible for development of new methods of birth control. Continued research and testing along these lines may lead to the development of contraceptives based on inhibitory analogues of LH-RH that could be conveniently applied as a nasal spray and that could be free of undesirable side effects.

Original languageEnglish
Pages (from-to)318-324
Number of pages7
JournalInternational Journal of Gynecology and Obstetrics
Volume18
Issue number5
StatePublished - Dec 1 1980
Externally publishedYes

Fingerprint

Hormone Antagonists
Gonadotropin-Releasing Hormone
Contraception
Nasal Sprays
Contraceptive Agents
Research

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

LH-RH agonists and antagonists. / Schally, Andrew V; Coy, D. H.; Arimura, A.

In: International Journal of Gynecology and Obstetrics, Vol. 18, No. 5, 01.12.1980, p. 318-324.

Research output: Contribution to journalArticle

Schally, AV, Coy, DH & Arimura, A 1980, 'LH-RH agonists and antagonists', International Journal of Gynecology and Obstetrics, vol. 18, no. 5, pp. 318-324.
Schally, Andrew V ; Coy, D. H. ; Arimura, A. / LH-RH agonists and antagonists. In: International Journal of Gynecology and Obstetrics. 1980 ; Vol. 18, No. 5. pp. 318-324.
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