Levodopa-responsive parkinsonism in a patient with Down's syndrome

Carlos Singer, J. Sanchez-Ramos, W. J. Weiner

Research output: Contribution to journal › Article

3 Citations (Scopus)

Abstract

We report a patient with Down's syndrome (DS) who developed progressive parkinsonian symptomatology at the age of 43 years. His parkinsonism was responsive to levodopa/carbidopa, but he developed end of dose wearing off. We discuss basal ganglia and dopamine abnormalities in DS and suggest that DS may be associated with parkinsonism.

Original languageEnglish
Pages (from-to)247-248
Number of pages2
JournalEuropean Neurology
Volume30
Issue number5
StatePublished - Jan 1 1990

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Parkinsonian Disorders
Levodopa
Down Syndrome
Basal Ganglia
Dopamine

Keywords

  • Down's syndrome
  • Parkinson's disease
  • Parkinsonism
  • Trisomy 21

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Singer, C., Sanchez-Ramos, J., & Weiner, W. J. (1990). Levodopa-responsive parkinsonism in a patient with Down's syndrome. European Neurology, 30(5), 247-248.

Levodopa-responsive parkinsonism in a patient with Down's syndrome. / Singer, Carlos; Sanchez-Ramos, J.; Weiner, W. J.

In: European Neurology, Vol. 30, No. 5, 01.01.1990, p. 247-248.

Research output: Contribution to journal › Article

Singer, C, Sanchez-Ramos, J & Weiner, WJ 1990, 'Levodopa-responsive parkinsonism in a patient with Down's syndrome', European Neurology, vol. 30, no. 5, pp. 247-248.
Singer C, Sanchez-Ramos J, Weiner WJ. Levodopa-responsive parkinsonism in a patient with Down's syndrome. European Neurology. 1990 Jan 1;30(5):247-248.
Singer, Carlos ; Sanchez-Ramos, J. ; Weiner, W. J. / Levodopa-responsive parkinsonism in a patient with Down's syndrome. In: European Neurology. 1990 ; Vol. 30, No. 5. pp. 247-248.
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