Levodopa, melanoma, and Parkinson's disease

William J. Weiner, Carlos Singer, Juan R. Sanchez-Ramos, James N. Goldenberg

Research output: Contribution to journalArticlepeer-review

26 Scopus citations


Previous reports and the Physicians' Desk Reference caution against the use of levodopa in Parkinson's disease (PD) patients with melanoma. A critical review of the literature reveals only anecdotal evidence to support a link between levodopa and melanoma. In fact, levodopa has an antitumor effect on melanoma. We report nine patients with PD and melanoma who were treated with levodopa/carbidopa (L/C). Current evidence suggests that L/C can be used safely in PD patients with a history of melanoma.

Original languageEnglish (US)
Pages (from-to)674-677
Number of pages4
Issue number4
StatePublished - Apr 1993

ASJC Scopus subject areas

  • Clinical Neurology


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