Leiomyosarcoma in urinary bladder after cyclophosphamide therapy for retinoblastoma and review of bladder sarcomas

Dipen J. Parekh, Charlie Jung, Jeffery O’conner, Sajal Dutta, Ernest R. Smith

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31 Scopus citations

Abstract

We report an unusual case of a leiomyosarcoma of the urinary bladder after chemotherapy for retinoblastoma and the results of a review of the published reports of bladder sarcomas. A 22-year-old man presented with hematuria and was found to have a mass in his urinary bladder on computed tomography. Transurethral resection of the mass revealed a leiomyosarcoma. The patient underwent radical cystectomy and an ileal conduit was created. The final pathologic examination confirmed high-grade leiomyosarcoma. Prospective randomized combination trials similar to the Intergroup Rhabdomyosarcoma Study in the pediatric population are necessary to better understand and manage these potentially curable sarcomas.

Original languageEnglish (US)
Pages (from-to)164xii-164xiv
JournalUrology
Volume60
Issue number1
DOIs
StatePublished - Jan 1 2002

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ASJC Scopus subject areas

  • Urology

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