With the increasing number of ontologies being designed to represent and manage knowledge in all sorts of sectors, ontology alignment and integration become more and more important in aggregating intelligent efforts on homogenous and heterogeneous data. From the computational perspective, it is challenging due to the ubiquitous existence of diverse classifications of same data. In this paper, we propose an active ontology integration and alignment system, which plugs in expandable learning reference context pool. In the reference context pool, we have integrated WordNet, MeSH, and external curated mapping sources (ICD9 to SNOMEDCT) with an extension to injecting UMLS. The active ontology integration and alignment system takes account of not only subsumption tree but also directed acyclic graph underlying ontologies. It allows 1) finding exact one-to-one matching terms of pairwise ontologies, 2) finding inexact one-to-one term mappings, where two terms have at least a concept in common on basis of the lexical context, and 3) finding one-to-many concept mappings, where one concept can be lexically mapped to the combination of multiple exclusive concepts.