TY - JOUR
T1 - Learning and memory in aging combat veterans with PTSD
AU - Yehuda, Rachel
AU - Golier, Julia A.
AU - Tischler, Lisa
AU - Stavitsky, Karina
AU - Harvey, Philip D.
N1 - Funding Information:
Received 26 January 2004; accepted 16 March 2004. This work was supported by VA Merit Funding to RY and JG and in part by a grant (5 M01 RR00071) for the Mount Sinai General Clinical Research Centre from the National Center for Research Resources, National Institute of Health. Address correspondence to Rachel Yehuda, Ph.D., Bronx VA OOMH, 130 West Kingsbridge Road, Bronx, NY 10468. E-mail: Rachel.Yehuda@med.va.gov
PY - 2005/5
Y1 - 2005/5
N2 - The California Verbal Learning Test (CVLT) was administered to examine learning and memory performance in aging combat veterans with (n=30) and without PTSD (n=20), and veterans unexposed to combat (n=15). Combat veterans with PTSD (PTSD+) showed many impairments compared to non-exposed veterans, but only long-delay free recall consistently discriminated the PTSD+ group from combat-exposed subjects without PTSD (PTSD-), when data were corrected for subscale scores on the WAIS (Vocabulary, Block Design). Alterations in total learning were associated with PTSD when controlling for substance abuse and depression. Two contrast measures, proactive interference and recognition hits, distinguished combat from noncombat veterans, and may be related to trauma exposure. Impairments in total learning are similar to what has been observed in Holocaust survivors. However, increased severity of rapid forgetting may be a specific alteration in older combat veterans, likely reflecting aspects of both combat exposure and aging.
AB - The California Verbal Learning Test (CVLT) was administered to examine learning and memory performance in aging combat veterans with (n=30) and without PTSD (n=20), and veterans unexposed to combat (n=15). Combat veterans with PTSD (PTSD+) showed many impairments compared to non-exposed veterans, but only long-delay free recall consistently discriminated the PTSD+ group from combat-exposed subjects without PTSD (PTSD-), when data were corrected for subscale scores on the WAIS (Vocabulary, Block Design). Alterations in total learning were associated with PTSD when controlling for substance abuse and depression. Two contrast measures, proactive interference and recognition hits, distinguished combat from noncombat veterans, and may be related to trauma exposure. Impairments in total learning are similar to what has been observed in Holocaust survivors. However, increased severity of rapid forgetting may be a specific alteration in older combat veterans, likely reflecting aspects of both combat exposure and aging.
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U2 - 10.1080/138033990520223
DO - 10.1080/138033990520223
M3 - Article
C2 - 15962694
AN - SCOPUS:17144426641
VL - 27
SP - 504
EP - 515
JO - Journal of Clinical and Experimental Neuropsychology
JF - Journal of Clinical and Experimental Neuropsychology
SN - 1380-3395
IS - 4
ER -