Lead resistance and sensitivity in Staphylococcus aureus

Hillel S. Levinson, Inga Mahler, Patricia Blackwelder, Terri Hood

Research output: Contribution to journalArticlepeer-review

63 Scopus citations


Five lead-resistant strains of Staphylococcus aureus were isolated. Plasmid-free lead-sensitive variants were obtained from the three plasmid-bearing strains. Lead-resistant strains tolerated an approximately 600 x higher Pb(NO3)2 concentration than lead-sensitive strains. Both types of strains initially bound lead, but only the resistant strains accumulated the metal as an intracellular lead-phosphate.

Original languageEnglish (US)
Pages (from-to)421-425
Number of pages5
JournalFEMS microbiology letters
Issue number3
StatePublished - Dec 15 1996


  • lead resistance
  • lead uptake
  • Staphylococcus aureus

ASJC Scopus subject areas

  • Microbiology
  • Molecular Biology
  • Genetics


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