TY - JOUR
T1 - Late restenosis after emergent coronary angioplasty for acute myocardial infarction
T2 - Comparison with elective coronary angioplasty
AU - Simonton, Charles A.
AU - Mark, Daniel B.
AU - Hinohara, Tomoaki
AU - Rendall, David S.
AU - Phillips, Harry R.
AU - Peter, Robert H.
AU - Behar, Victor S.
AU - Kong, Yihong
AU - O'Callaghan, William G.
AU - O'Connor, Christopher
AU - Califf, Robert M.
AU - Stack, Richard S.
N1 - Copyright:
Copyright 2014 Elsevier B.V., All rights reserved.
PY - 1988/4
Y1 - 1988/4
N2 - The late restenosis rate after emergent percutaneous transluminal coronary angioplasty for acute myocardial infarction was assessed by performing outpatient fallow-up cardiac catheterization in 79 (87%) of 91 consecutive patients who had been discharged from the hospital with a successful coronary angioplasty. The majority of patients (90%) received high dose intravenous thrambolytic therapy with streptokinase in addition to angioplasty. Similar follow-up data were obtained in 206 (90%) of 228 consecutive patients who had successful elective angioplasty during the same period. The interval from angioplasty to follow-up was 28 ± 9 weeks for the myocardial infarction group and 30 ± 11 weeks for the elective group. Basetine clinical variables were similar for both the myocardial infarction and elective groups except for a higher percentage of men in the infarction group (81 versus 63%, p = 0.001). The number of coronary lesions undergoing angioplasty and the incidence of intimal dissection were similar, but multivessel angioplasty was more common in the elective group (13 versus 4%, p = 0.02). The rate of in-hospital reocclusion was higher in the patients receiving angioplasty for myocardial infarction (13 versus 2%, p = 0.0001). At the time of late follow-up after hospital discharge, the patients with myocardial infarction were more often asymptomatic (79 versus 55%, p = 0.0001), and the rate of angiographic coronary restenosis was lower for the infarction group both overall (19 versus 35%, p = 0.006) and when multivessel angioplasty patients were excluded (19 versus 33%, p = 0.01). These findings indicate that the rate of early reocclusion is higher and that of long-term restenosis is lower after successful emergent coronary angioplasty in the setting of thrombolytic therapy with streptokinase for acute myocardial infarction than after elective angioplasty.
AB - The late restenosis rate after emergent percutaneous transluminal coronary angioplasty for acute myocardial infarction was assessed by performing outpatient fallow-up cardiac catheterization in 79 (87%) of 91 consecutive patients who had been discharged from the hospital with a successful coronary angioplasty. The majority of patients (90%) received high dose intravenous thrambolytic therapy with streptokinase in addition to angioplasty. Similar follow-up data were obtained in 206 (90%) of 228 consecutive patients who had successful elective angioplasty during the same period. The interval from angioplasty to follow-up was 28 ± 9 weeks for the myocardial infarction group and 30 ± 11 weeks for the elective group. Basetine clinical variables were similar for both the myocardial infarction and elective groups except for a higher percentage of men in the infarction group (81 versus 63%, p = 0.001). The number of coronary lesions undergoing angioplasty and the incidence of intimal dissection were similar, but multivessel angioplasty was more common in the elective group (13 versus 4%, p = 0.02). The rate of in-hospital reocclusion was higher in the patients receiving angioplasty for myocardial infarction (13 versus 2%, p = 0.0001). At the time of late follow-up after hospital discharge, the patients with myocardial infarction were more often asymptomatic (79 versus 55%, p = 0.0001), and the rate of angiographic coronary restenosis was lower for the infarction group both overall (19 versus 35%, p = 0.006) and when multivessel angioplasty patients were excluded (19 versus 33%, p = 0.01). These findings indicate that the rate of early reocclusion is higher and that of long-term restenosis is lower after successful emergent coronary angioplasty in the setting of thrombolytic therapy with streptokinase for acute myocardial infarction than after elective angioplasty.
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U2 - 10.1016/0735-1097(88)90198-2
DO - 10.1016/0735-1097(88)90198-2
M3 - Article
C2 - 2965171
AN - SCOPUS:0023928407
VL - 11
SP - 698
EP - 705
JO - Journal of the American College of Cardiology
JF - Journal of the American College of Cardiology
SN - 0735-1097
IS - 4
ER -