Abstract
The late restenosis rate after emergent percutaneous transluminal coronary angioplasty for acute myocardial infarction was assessed by performing outpatient fallow-up cardiac catheterization in 79 (87%) of 91 consecutive patients who had been discharged from the hospital with a successful coronary angioplasty. The majority of patients (90%) received high dose intravenous thrambolytic therapy with streptokinase in addition to angioplasty. Similar follow-up data were obtained in 206 (90%) of 228 consecutive patients who had successful elective angioplasty during the same period. The interval from angioplasty to follow-up was 28 ± 9 weeks for the myocardial infarction group and 30 ± 11 weeks for the elective group. Basetine clinical variables were similar for both the myocardial infarction and elective groups except for a higher percentage of men in the infarction group (81 versus 63%, p = 0.001). The number of coronary lesions undergoing angioplasty and the incidence of intimal dissection were similar, but multivessel angioplasty was more common in the elective group (13 versus 4%, p = 0.02). The rate of in-hospital reocclusion was higher in the patients receiving angioplasty for myocardial infarction (13 versus 2%, p = 0.0001). At the time of late follow-up after hospital discharge, the patients with myocardial infarction were more often asymptomatic (79 versus 55%, p = 0.0001), and the rate of angiographic coronary restenosis was lower for the infarction group both overall (19 versus 35%, p = 0.006) and when multivessel angioplasty patients were excluded (19 versus 33%, p = 0.01). These findings indicate that the rate of early reocclusion is higher and that of long-term restenosis is lower after successful emergent coronary angioplasty in the setting of thrombolytic therapy with streptokinase for acute myocardial infarction than after elective angioplasty.
| Original language | English |
|---|---|
| Pages (from-to) | 698-705 |
| Number of pages | 8 |
| Journal | Journal of the American College of Cardiology |
| Volume | 11 |
| Issue number | 4 |
| DOIs | |
| State | Published - Jan 1 1988 |
| Externally published | Yes |
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Late restenosis after emergent coronary angioplasty for acute myocardial infarction : Comparison with elective coronary angioplasty. / Simonton, Charles A.; Mark, Daniel B.; Hinohara, Tomoaki; Rendall, David S.; Phillips, Harry R.; Peter, Robert H.; Behar, Victor S.; Kong, Yihong; O'Callaghan, William G.; O'Connor, Christopher; Califf, Robert M.; Stack, Richard S.
In: Journal of the American College of Cardiology, Vol. 11, No. 4, 01.01.1988, p. 698-705.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Late restenosis after emergent coronary angioplasty for acute myocardial infarction
T2 - Comparison with elective coronary angioplasty
AU - Simonton, Charles A.
AU - Mark, Daniel B.
AU - Hinohara, Tomoaki
AU - Rendall, David S.
AU - Phillips, Harry R.
AU - Peter, Robert H.
AU - Behar, Victor S.
AU - Kong, Yihong
AU - O'Callaghan, William G.
AU - O'Connor, Christopher
AU - Califf, Robert M.
AU - Stack, Richard S.
PY - 1988/1/1
Y1 - 1988/1/1
N2 - The late restenosis rate after emergent percutaneous transluminal coronary angioplasty for acute myocardial infarction was assessed by performing outpatient fallow-up cardiac catheterization in 79 (87%) of 91 consecutive patients who had been discharged from the hospital with a successful coronary angioplasty. The majority of patients (90%) received high dose intravenous thrambolytic therapy with streptokinase in addition to angioplasty. Similar follow-up data were obtained in 206 (90%) of 228 consecutive patients who had successful elective angioplasty during the same period. The interval from angioplasty to follow-up was 28 ± 9 weeks for the myocardial infarction group and 30 ± 11 weeks for the elective group. Basetine clinical variables were similar for both the myocardial infarction and elective groups except for a higher percentage of men in the infarction group (81 versus 63%, p = 0.001). The number of coronary lesions undergoing angioplasty and the incidence of intimal dissection were similar, but multivessel angioplasty was more common in the elective group (13 versus 4%, p = 0.02). The rate of in-hospital reocclusion was higher in the patients receiving angioplasty for myocardial infarction (13 versus 2%, p = 0.0001). At the time of late follow-up after hospital discharge, the patients with myocardial infarction were more often asymptomatic (79 versus 55%, p = 0.0001), and the rate of angiographic coronary restenosis was lower for the infarction group both overall (19 versus 35%, p = 0.006) and when multivessel angioplasty patients were excluded (19 versus 33%, p = 0.01). These findings indicate that the rate of early reocclusion is higher and that of long-term restenosis is lower after successful emergent coronary angioplasty in the setting of thrombolytic therapy with streptokinase for acute myocardial infarction than after elective angioplasty.
AB - The late restenosis rate after emergent percutaneous transluminal coronary angioplasty for acute myocardial infarction was assessed by performing outpatient fallow-up cardiac catheterization in 79 (87%) of 91 consecutive patients who had been discharged from the hospital with a successful coronary angioplasty. The majority of patients (90%) received high dose intravenous thrambolytic therapy with streptokinase in addition to angioplasty. Similar follow-up data were obtained in 206 (90%) of 228 consecutive patients who had successful elective angioplasty during the same period. The interval from angioplasty to follow-up was 28 ± 9 weeks for the myocardial infarction group and 30 ± 11 weeks for the elective group. Basetine clinical variables were similar for both the myocardial infarction and elective groups except for a higher percentage of men in the infarction group (81 versus 63%, p = 0.001). The number of coronary lesions undergoing angioplasty and the incidence of intimal dissection were similar, but multivessel angioplasty was more common in the elective group (13 versus 4%, p = 0.02). The rate of in-hospital reocclusion was higher in the patients receiving angioplasty for myocardial infarction (13 versus 2%, p = 0.0001). At the time of late follow-up after hospital discharge, the patients with myocardial infarction were more often asymptomatic (79 versus 55%, p = 0.0001), and the rate of angiographic coronary restenosis was lower for the infarction group both overall (19 versus 35%, p = 0.006) and when multivessel angioplasty patients were excluded (19 versus 33%, p = 0.01). These findings indicate that the rate of early reocclusion is higher and that of long-term restenosis is lower after successful emergent coronary angioplasty in the setting of thrombolytic therapy with streptokinase for acute myocardial infarction than after elective angioplasty.
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UR - http://www.scopus.com/inward/citedby.url?scp=0023928407&partnerID=8YFLogxK
U2 - 10.1016/0735-1097(88)90198-2
DO - 10.1016/0735-1097(88)90198-2
M3 - Article
C2 - 2965171
AN - SCOPUS:0023928407
VL - 11
SP - 698
EP - 705
JO - Journal of the American College of Cardiology
JF - Journal of the American College of Cardiology
SN - 0735-1097
IS - 4
ER -