Late-onset neurologic disease in glutaryl-CoA dehydrogenase deficiency

S. Külkens, I. Harting, S. Sauer, J. Zschocke, G. F. Hoffmann, S. Gruber, O. A. Bodamer, Stefan Kölker

Research output: Contribution to journalArticle

55 Citations (Scopus)

Abstract

Neurologic disease in glutaryl-CoA dehydrogenase (GCDH) deficiency usually presents with acute encephalopathic crises before 2 years of age. The authors report two previously asymptomatic patients with macrocephaly presenting with progressive neurologic deterioration and a severe leukoencephalopathy during adolescence or adulthood.

Original languageEnglish
Pages (from-to)2142-2144
Number of pages3
JournalNeurology
Volume64
Issue number12
DOIs
StatePublished - Jun 28 2005

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Megalencephaly
Leukoencephalopathies
Nervous System Diseases
Nervous System
Glutaric Acidemia I
Late Onset Disorders

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Külkens, S., Harting, I., Sauer, S., Zschocke, J., Hoffmann, G. F., Gruber, S., ... Kölker, S. (2005). Late-onset neurologic disease in glutaryl-CoA dehydrogenase deficiency. Neurology, 64(12), 2142-2144. https://doi.org/10.1212/01.WNL.0000167428.12417.B2

Late-onset neurologic disease in glutaryl-CoA dehydrogenase deficiency. / Külkens, S.; Harting, I.; Sauer, S.; Zschocke, J.; Hoffmann, G. F.; Gruber, S.; Bodamer, O. A.; Kölker, Stefan.

In: Neurology, Vol. 64, No. 12, 28.06.2005, p. 2142-2144.

Research output: Contribution to journalArticle

Külkens, S, Harting, I, Sauer, S, Zschocke, J, Hoffmann, GF, Gruber, S, Bodamer, OA & Kölker, S 2005, 'Late-onset neurologic disease in glutaryl-CoA dehydrogenase deficiency', Neurology, vol. 64, no. 12, pp. 2142-2144. https://doi.org/10.1212/01.WNL.0000167428.12417.B2
Külkens S, Harting I, Sauer S, Zschocke J, Hoffmann GF, Gruber S et al. Late-onset neurologic disease in glutaryl-CoA dehydrogenase deficiency. Neurology. 2005 Jun 28;64(12):2142-2144. https://doi.org/10.1212/01.WNL.0000167428.12417.B2
Külkens, S. ; Harting, I. ; Sauer, S. ; Zschocke, J. ; Hoffmann, G. F. ; Gruber, S. ; Bodamer, O. A. ; Kölker, Stefan. / Late-onset neurologic disease in glutaryl-CoA dehydrogenase deficiency. In: Neurology. 2005 ; Vol. 64, No. 12. pp. 2142-2144.
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