Lasers and light sources to activate fibroblasts

Christopher Spock, Andrei I. Metelitsa, Joely Kaufman, Jeremy B. Green

Research output: Contribution to journalArticle

Abstract

There is a decrease in normal collagen in aged and sun-damaged skin. Neocollagenesis can promote a more youthful appearance. A key target in the mitigation of the pathophysiology of photoaging is fibroblasts. Various therapeutic modalities can be employed, including topical retinoids, dermabrasion, radiofrequency or ultrasound energy, and filler injections. This review focuses on the molecular-level effects of lasers and light sources to activate fibroblasts. Fractional ablative and nonablative resurfacing lasers are the gold standard for stimulating aged fibroblasts and inducing neocollagenesis; however, other laser and light modalities can be employed to activate quiescent fibroblasts.

Original languageEnglish (US)
Pages (from-to)27-33
Number of pages7
JournalCosmetic Dermatology
Volume25
Issue number1
StatePublished - Jan 2012

Fingerprint

Lasers
Fibroblasts
Light
Dermabrasion
Retinoids
Solar System
Collagen
Skin
Injections
Therapeutics

ASJC Scopus subject areas

  • Dermatology
  • Surgery

Cite this

Spock, C., Metelitsa, A. I., Kaufman, J., & Green, J. B. (2012). Lasers and light sources to activate fibroblasts. Cosmetic Dermatology, 25(1), 27-33.

Lasers and light sources to activate fibroblasts. / Spock, Christopher; Metelitsa, Andrei I.; Kaufman, Joely; Green, Jeremy B.

In: Cosmetic Dermatology, Vol. 25, No. 1, 01.2012, p. 27-33.

Research output: Contribution to journalArticle

Spock, C, Metelitsa, AI, Kaufman, J & Green, JB 2012, 'Lasers and light sources to activate fibroblasts', Cosmetic Dermatology, vol. 25, no. 1, pp. 27-33.
Spock C, Metelitsa AI, Kaufman J, Green JB. Lasers and light sources to activate fibroblasts. Cosmetic Dermatology. 2012 Jan;25(1):27-33.
Spock, Christopher ; Metelitsa, Andrei I. ; Kaufman, Joely ; Green, Jeremy B. / Lasers and light sources to activate fibroblasts. In: Cosmetic Dermatology. 2012 ; Vol. 25, No. 1. pp. 27-33.
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