Laser-induced choroidal neovascularization detected on optical coherence tomography angiography in patients with diabetic retinopathy

Prashanth G. Iyer; Philip J. Rosenfeld; Harry W. Flynn

doi:10.1016/j.ajoc.2022.101316

Laser-induced choroidal neovascularization detected on optical coherence tomography angiography in patients with diabetic retinopathy

Prashanth G. Iyer, Philip J. Rosenfeld, Harry W. Flynn

Research output: Contribution to journal › Article › peer-review

Abstract

Purpose: To report two cases of laser-induced choroidal neovascularization (CNV) using swept source optical coherence tomography (SS-OCTA) imaging in patients with proliferative diabetic retinopathy. Observations: Two patients developed CNV adjacent to laser scars, and these neovascular lesions were detected on SS-OCTA imaging. Historically, both patients had subretinal fluid associated with these lesions. Visual acuity for both patients was 20/25 in the affected eyes. Both patients were observed over multiple years with stable CNV and visual acuity. Conclusions and importance: SS-OCTA was able to detect laser-induced CNV in a rapid and non-invasive manner. When there is no foveal involvement and excellent visual acuity, we recommend close observation since the CNV may not progress.

Original language	English (US)
Article number	101316
Journal	American Journal of Ophthalmology Case Reports
Volume	25
DOIs	https://doi.org/10.1016/j.ajoc.2022.101316
State	Published - Mar 2022
Externally published	Yes

Keywords

Choroidal neovascularization (CNV)
Diabetic retinopathy
Laser
Photocoagulation
Swep -source optical coherence tomography angiography (SS-OCTA)

ASJC Scopus subject areas

Ophthalmology

Access to Document

10.1016/j.ajoc.2022.101316

Cite this

@article{661e3cb1df334d1f92560d5e1ccdeed9,

title = "Laser-induced choroidal neovascularization detected on optical coherence tomography angiography in patients with diabetic retinopathy",

abstract = "Purpose: To report two cases of laser-induced choroidal neovascularization (CNV) using swept source optical coherence tomography (SS-OCTA) imaging in patients with proliferative diabetic retinopathy. Observations: Two patients developed CNV adjacent to laser scars, and these neovascular lesions were detected on SS-OCTA imaging. Historically, both patients had subretinal fluid associated with these lesions. Visual acuity for both patients was 20/25 in the affected eyes. Both patients were observed over multiple years with stable CNV and visual acuity. Conclusions and importance: SS-OCTA was able to detect laser-induced CNV in a rapid and non-invasive manner. When there is no foveal involvement and excellent visual acuity, we recommend close observation since the CNV may not progress.",

keywords = "Choroidal neovascularization (CNV), Diabetic retinopathy, Laser, Photocoagulation, Swep -source optical coherence tomography angiography (SS-OCTA)",

author = "Iyer, {Prashanth G.} and Rosenfeld, {Philip J.} and Flynn, {Harry W.}",

note = "Funding Information: Dr. Rosenfeld also receives additional research funding from Stealth BioTherapeutics . He is also a consultant for Apellis, Biogen, Boehringer-Ingelheim, Carl Zeiss Meditec, Chengdu Kanghong Biotech, EyePoint, Ocunexus Therapeutics, Ocudyne, and Unity Biotechnology. He also has equity interest in Apellis, Valitor, Verana Health, and Ocudyne. Funding Information: Dr. Rosenfeld also receives additional research funding from Stealth BioTherapeutics. He is also a consultant for Apellis, Biogen, Boehringer-Ingelheim, Carl Zeiss Meditec, Chengdu Kanghong Biotech, EyePoint, Ocunexus Therapeutics, Ocudyne, and Unity Biotechnology. He also has equity interest in Apellis, Valitor, Verana Health, and Ocudyne. Publisher Copyright: {\textcopyright} 2022",

year = "2022",

month = mar,

doi = "10.1016/j.ajoc.2022.101316",

language = "English (US)",

volume = "25",

journal = "American Journal of Ophthalmology Case Reports",

issn = "2451-9936",

publisher = "Elsevier Inc.",

}

TY - JOUR

T1 - Laser-induced choroidal neovascularization detected on optical coherence tomography angiography in patients with diabetic retinopathy

AU - Iyer, Prashanth G.

AU - Rosenfeld, Philip J.

AU - Flynn, Harry W.

N1 - Funding Information: Dr. Rosenfeld also receives additional research funding from Stealth BioTherapeutics . He is also a consultant for Apellis, Biogen, Boehringer-Ingelheim, Carl Zeiss Meditec, Chengdu Kanghong Biotech, EyePoint, Ocunexus Therapeutics, Ocudyne, and Unity Biotechnology. He also has equity interest in Apellis, Valitor, Verana Health, and Ocudyne. Funding Information: Dr. Rosenfeld also receives additional research funding from Stealth BioTherapeutics. He is also a consultant for Apellis, Biogen, Boehringer-Ingelheim, Carl Zeiss Meditec, Chengdu Kanghong Biotech, EyePoint, Ocunexus Therapeutics, Ocudyne, and Unity Biotechnology. He also has equity interest in Apellis, Valitor, Verana Health, and Ocudyne. Publisher Copyright: © 2022

PY - 2022/3

Y1 - 2022/3

N2 - Purpose: To report two cases of laser-induced choroidal neovascularization (CNV) using swept source optical coherence tomography (SS-OCTA) imaging in patients with proliferative diabetic retinopathy. Observations: Two patients developed CNV adjacent to laser scars, and these neovascular lesions were detected on SS-OCTA imaging. Historically, both patients had subretinal fluid associated with these lesions. Visual acuity for both patients was 20/25 in the affected eyes. Both patients were observed over multiple years with stable CNV and visual acuity. Conclusions and importance: SS-OCTA was able to detect laser-induced CNV in a rapid and non-invasive manner. When there is no foveal involvement and excellent visual acuity, we recommend close observation since the CNV may not progress.

AB - Purpose: To report two cases of laser-induced choroidal neovascularization (CNV) using swept source optical coherence tomography (SS-OCTA) imaging in patients with proliferative diabetic retinopathy. Observations: Two patients developed CNV adjacent to laser scars, and these neovascular lesions were detected on SS-OCTA imaging. Historically, both patients had subretinal fluid associated with these lesions. Visual acuity for both patients was 20/25 in the affected eyes. Both patients were observed over multiple years with stable CNV and visual acuity. Conclusions and importance: SS-OCTA was able to detect laser-induced CNV in a rapid and non-invasive manner. When there is no foveal involvement and excellent visual acuity, we recommend close observation since the CNV may not progress.

KW - Choroidal neovascularization (CNV)

KW - Diabetic retinopathy

KW - Laser

KW - Photocoagulation

KW - Swep -source optical coherence tomography angiography (SS-OCTA)

UR - http://www.scopus.com/inward/record.url?scp=85123639916&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85123639916&partnerID=8YFLogxK

U2 - 10.1016/j.ajoc.2022.101316

DO - 10.1016/j.ajoc.2022.101316

M3 - Article

AN - SCOPUS:85123639916

VL - 25

JO - American Journal of Ophthalmology Case Reports

JF - American Journal of Ophthalmology Case Reports

SN - 2451-9936

M1 - 101316

ER -

Laser-induced choroidal neovascularization detected on optical coherence tomography angiography in patients with diabetic retinopathy

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this