Laser Ablation for Cerebral Metastases

Evan Luther, Samuel Mansour, Nikolas Echeverry, David McCarthy, Daniel G. Eichberg, Ashish Shah, Ahmed Nada, Katherine Berry, Michael Kader, Michael Ivan, Ricardo Komotar

Research output: Contribution to journalReview articlepeer-review


Laser interstitial thermal therapy is a minimally invasive surgical alternative to craniotomy that uses laser light through a fiber optic probe placed within a target lesion to create thermal tissue damage, resulting in cellular death. It is used in neuro-oncology to treat inaccessible lesions and obviate morbidity in high-risk patients. Overall complication rates and outcome measures are comparable with those seen in radiation and/or craniotomy. Laser interstitial thermal therapy can be an effective option for recurrent brain metastases. Prospective, randomized trials must be performed to evaluate the efficacy of laser interstitial thermal therapy as a primary treatment for brain metastases.

Original languageEnglish (US)
Pages (from-to)537-547
Number of pages11
JournalNeurosurgery clinics of North America
Issue number4
StatePublished - Oct 2020


  • Brain metastasis
  • Brain tumor
  • Laser ablation
  • Laser interstitial thermal therapy
  • Metastases
  • Minimally invasive surgery
  • Neuro-oncology
  • Oncology

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology


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