Abstract
Laser interstitial thermal therapy is a minimally invasive surgical alternative to craniotomy that uses laser light through a fiber optic probe placed within a target lesion to create thermal tissue damage, resulting in cellular death. It is used in neuro-oncology to treat inaccessible lesions and obviate morbidity in high-risk patients. Overall complication rates and outcome measures are comparable with those seen in radiation and/or craniotomy. Laser interstitial thermal therapy can be an effective option for recurrent brain metastases. Prospective, randomized trials must be performed to evaluate the efficacy of laser interstitial thermal therapy as a primary treatment for brain metastases.
Original language | English (US) |
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Pages (from-to) | 537-547 |
Number of pages | 11 |
Journal | Neurosurgery clinics of North America |
Volume | 31 |
Issue number | 4 |
DOIs | |
State | Published - Oct 2020 |
Keywords
- Brain metastasis
- Brain tumor
- Laser ablation
- Laser interstitial thermal therapy
- Metastases
- Minimally invasive surgery
- Neuro-oncology
- Oncology
ASJC Scopus subject areas
- Surgery
- Clinical Neurology