Laparoscopic radiofrequency thermal ablation of hepatocarcinoma: Preliminary experience

Orlando Goletti, Riccardo Lencioni, Nicola Armillotta, Adolfo Puglisi, Piero Vincenzo Lippolis, Luca Lorenzetti, Daniela Cioni, Barbara Musco, Carlo Bartolozzi, Enrico Cavina

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

The objective was to evaluate the feasibility, safety, and effectiveness of radiofrequency thermal ablation (RFT), performed during laparoscopy with a cooledtip electrode needle, in the treatment of neoplastic hepatic focal lesions. Seven patients with hepatocarcinoma (10 hepatic lesions) were treated during laparoscopy with RFT using a 100-watt RF generator and 17-gauge, dual-lumen, cooled-tip electrode needles with a 3-cm exposed tip. The mean exposure time was 12 minutes for each needle insertion. Spiral computed tomography scanning detected complete tumor necrosis in nine lesions; in one lesion, peripheral neoplastic tissue was detected, and percutaneous RFT was performed. Two patients during follow-up developed two new neoplastic lesions, treated with percutaneous ethanol injection. No recurrences of the treated lesions were seen after 6 months of follow up. Intraoperative RFT with a cooled-tip electrode needle is a safe and effective local treatment of hepatic focal lesions during laparoscopic surgery. Possible indications are large hepatocarcinoma (>5 cm), superficial lesions, multiple lesions, or tumor located near vascular or biliary structures.

Original languageEnglish (US)
Pages (from-to)284-290
Number of pages7
JournalSurgical Laparoscopy, Endoscopy and Percutaneous Techniques
Volume10
Issue number5
StatePublished - 2000
Externally publishedYes

Fingerprint

Needles
Hot Temperature
Laparoscopy
Electrodes
Liver
Spiral Computed Tomography
Blood Vessels
Neoplasms
Ethanol
Necrosis
Safety
Recurrence
Injections
Therapeutics

Keywords

  • Liver neoplasms, laparoscopy
  • Liver neoplasms, secondary
  • Liver neoplasms, therapy
  • Liver, interventional procedure
  • Radiofrequency ablation

ASJC Scopus subject areas

  • Surgery

Cite this

Goletti, O., Lencioni, R., Armillotta, N., Puglisi, A., Lippolis, P. V., Lorenzetti, L., ... Cavina, E. (2000). Laparoscopic radiofrequency thermal ablation of hepatocarcinoma: Preliminary experience. Surgical Laparoscopy, Endoscopy and Percutaneous Techniques, 10(5), 284-290.

Laparoscopic radiofrequency thermal ablation of hepatocarcinoma : Preliminary experience. / Goletti, Orlando; Lencioni, Riccardo; Armillotta, Nicola; Puglisi, Adolfo; Lippolis, Piero Vincenzo; Lorenzetti, Luca; Cioni, Daniela; Musco, Barbara; Bartolozzi, Carlo; Cavina, Enrico.

In: Surgical Laparoscopy, Endoscopy and Percutaneous Techniques, Vol. 10, No. 5, 2000, p. 284-290.

Research output: Contribution to journalArticle

Goletti, O, Lencioni, R, Armillotta, N, Puglisi, A, Lippolis, PV, Lorenzetti, L, Cioni, D, Musco, B, Bartolozzi, C & Cavina, E 2000, 'Laparoscopic radiofrequency thermal ablation of hepatocarcinoma: Preliminary experience', Surgical Laparoscopy, Endoscopy and Percutaneous Techniques, vol. 10, no. 5, pp. 284-290.
Goletti O, Lencioni R, Armillotta N, Puglisi A, Lippolis PV, Lorenzetti L et al. Laparoscopic radiofrequency thermal ablation of hepatocarcinoma: Preliminary experience. Surgical Laparoscopy, Endoscopy and Percutaneous Techniques. 2000;10(5):284-290.
Goletti, Orlando ; Lencioni, Riccardo ; Armillotta, Nicola ; Puglisi, Adolfo ; Lippolis, Piero Vincenzo ; Lorenzetti, Luca ; Cioni, Daniela ; Musco, Barbara ; Bartolozzi, Carlo ; Cavina, Enrico. / Laparoscopic radiofrequency thermal ablation of hepatocarcinoma : Preliminary experience. In: Surgical Laparoscopy, Endoscopy and Percutaneous Techniques. 2000 ; Vol. 10, No. 5. pp. 284-290.
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