Laparoscopic radiofrequency thermal ablation of hepatocarcinoma: Preliminary experience

Orlando Goletti, Riccardo Lencioni, Nicola Armillotta, Adolfo Puglisi, Piero Vincenzo Lippolis, Luca Lorenzetti, Daniela Cioni, Barbara Musco, Carlo Bartolozzi, Enrico Cavina

Research output: Contribution to journalArticlepeer-review

31 Scopus citations


The objective was to evaluate the feasibility, safety, and effectiveness of radiofrequency thermal ablation (RFT), performed during laparoscopy with a cooledtip electrode needle, in the treatment of neoplastic hepatic focal lesions. Seven patients with hepatocarcinoma (10 hepatic lesions) were treated during laparoscopy with RFT using a 100-watt RF generator and 17-gauge, dual-lumen, cooled-tip electrode needles with a 3-cm exposed tip. The mean exposure time was 12 minutes for each needle insertion. Spiral computed tomography scanning detected complete tumor necrosis in nine lesions; in one lesion, peripheral neoplastic tissue was detected, and percutaneous RFT was performed. Two patients during follow-up developed two new neoplastic lesions, treated with percutaneous ethanol injection. No recurrences of the treated lesions were seen after 6 months of follow up. Intraoperative RFT with a cooled-tip electrode needle is a safe and effective local treatment of hepatic focal lesions during laparoscopic surgery. Possible indications are large hepatocarcinoma (>5 cm), superficial lesions, multiple lesions, or tumor located near vascular or biliary structures.

Original languageEnglish (US)
Pages (from-to)284-290
Number of pages7
JournalSurgical Laparoscopy, Endoscopy and Percutaneous Techniques
Issue number5
StatePublished - Oct 26 2000


  • Liver neoplasms, laparoscopy
  • Liver neoplasms, secondary
  • Liver neoplasms, therapy
  • Liver, interventional procedure
  • Radiofrequency ablation

ASJC Scopus subject areas

  • Surgery


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