Laparoscopic and histologic findings in patients with the human immunodeficiency virus

Lennox J. Jeffers; Isaac Alzate; Humberto Aguilar; K. Rajender Reddy; Victor Idrovo; Hugo Cheinquer; Fuad A. Hasan; Talley Parker; Carlos Montero; Gordon Dickinson; Eugene R. Schiff

doi:10.1016/S0016-5107(94)70159-8

Laparoscopic and histologic findings in patients with the human immunodeficiency virus

Lennox J. Jeffers, Isaac Alzate, Humberto Aguilar, K. Rajender Reddy, Victor Idrovo, Hugo Cheinquer, Fuad A. Hasan, Talley Parker, Carlos Montero, Gordon Dickinson, Eugene R. Schiff

Medicine

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

Hepatic dysfunction frequently develops in patients infected with the human immunodeficiency virus (HIV). This retrospective study was undertaken to determine the laparoscopic and histologic findings in a group of HIV- seropositive patients with or without the acquired immune deficiency syndrome (AIDS). Fifty-four patients, 44 with AIDS and 10 HIV-positive, underwent laparoscopic examination and visually guided biopsies for the assessment of clinical or biochemical evidence of liver injury. Significant abnormalities were detected in 31/44 (70%) AIDS patients and 3/10 (30%) HIV-positive patients. Overall, specific laparoscopic findings were described in 25/54 (46%). The most common findings were peritoneal involvement, massive intra- abdominal adhesions, focal lesions of the liver or spleen, and diffuse nodularity of the liver; these were usually related to opportunistic infections or neoplasms such as non-Hodgkin's lymphomas and Kaposi's sarcoma. No procedure-related deaths occurred. Laparoscopy is a safe and accurate method to detect underlying disease in a selected population of HIV- seropositive patients.

Original language	English (US)
Pages (from-to)	160-164
Number of pages	5
Journal	Gastrointestinal endoscopy
Volume	40
Issue number	2
DOIs	https://doi.org/10.1016/S0016-5107(94)70159-8
State	Published - Jan 1 1994

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging
Gastroenterology

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Laparoscopic and histologic findings in patients with the human immunodeficiency virus. / Jeffers, Lennox J.; Alzate, Isaac; Aguilar, Humberto; Reddy, K. Rajender; Idrovo, Victor; Cheinquer, Hugo; Hasan, Fuad A.; Parker, Talley; Montero, Carlos; Dickinson, Gordon ; Schiff, Eugene R.

In: Gastrointestinal endoscopy, Vol. 40, No. 2, 01.01.1994, p. 160-164.

Research output: Contribution to journal › Article › peer-review

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abstract = "Hepatic dysfunction frequently develops in patients infected with the human immunodeficiency virus (HIV). This retrospective study was undertaken to determine the laparoscopic and histologic findings in a group of HIV- seropositive patients with or without the acquired immune deficiency syndrome (AIDS). Fifty-four patients, 44 with AIDS and 10 HIV-positive, underwent laparoscopic examination and visually guided biopsies for the assessment of clinical or biochemical evidence of liver injury. Significant abnormalities were detected in 31/44 (70%) AIDS patients and 3/10 (30%) HIV-positive patients. Overall, specific laparoscopic findings were described in 25/54 (46%). The most common findings were peritoneal involvement, massive intra- abdominal adhesions, focal lesions of the liver or spleen, and diffuse nodularity of the liver; these were usually related to opportunistic infections or neoplasms such as non-Hodgkin's lymphomas and Kaposi's sarcoma. No procedure-related deaths occurred. Laparoscopy is a safe and accurate method to detect underlying disease in a selected population of HIV- seropositive patients.",

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AU - Idrovo, Victor

AU - Cheinquer, Hugo

AU - Hasan, Fuad A.

AU - Parker, Talley

AU - Montero, Carlos

AU - Dickinson, Gordon

AU - Schiff, Eugene R.

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N2 - Hepatic dysfunction frequently develops in patients infected with the human immunodeficiency virus (HIV). This retrospective study was undertaken to determine the laparoscopic and histologic findings in a group of HIV- seropositive patients with or without the acquired immune deficiency syndrome (AIDS). Fifty-four patients, 44 with AIDS and 10 HIV-positive, underwent laparoscopic examination and visually guided biopsies for the assessment of clinical or biochemical evidence of liver injury. Significant abnormalities were detected in 31/44 (70%) AIDS patients and 3/10 (30%) HIV-positive patients. Overall, specific laparoscopic findings were described in 25/54 (46%). The most common findings were peritoneal involvement, massive intra- abdominal adhesions, focal lesions of the liver or spleen, and diffuse nodularity of the liver; these were usually related to opportunistic infections or neoplasms such as non-Hodgkin's lymphomas and Kaposi's sarcoma. No procedure-related deaths occurred. Laparoscopy is a safe and accurate method to detect underlying disease in a selected population of HIV- seropositive patients.

AB - Hepatic dysfunction frequently develops in patients infected with the human immunodeficiency virus (HIV). This retrospective study was undertaken to determine the laparoscopic and histologic findings in a group of HIV- seropositive patients with or without the acquired immune deficiency syndrome (AIDS). Fifty-four patients, 44 with AIDS and 10 HIV-positive, underwent laparoscopic examination and visually guided biopsies for the assessment of clinical or biochemical evidence of liver injury. Significant abnormalities were detected in 31/44 (70%) AIDS patients and 3/10 (30%) HIV-positive patients. Overall, specific laparoscopic findings were described in 25/54 (46%). The most common findings were peritoneal involvement, massive intra- abdominal adhesions, focal lesions of the liver or spleen, and diffuse nodularity of the liver; these were usually related to opportunistic infections or neoplasms such as non-Hodgkin's lymphomas and Kaposi's sarcoma. No procedure-related deaths occurred. Laparoscopy is a safe and accurate method to detect underlying disease in a selected population of HIV- seropositive patients.

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