Abstract
The absence of carnitine in the diet of normal infants results in marked reduction of plasma carnitine levels. In order to evaluate the effects of L-carnitine supplementation of soybean formula, plasma and urine levels of free carnitine and acylcarnitine were compared in infants receiving carnitine-free soybean protein-based formula and the same formula supplemented with 50 and 250 nmol/ml L-carnitine. In infants receiving soybean formula with 50 nmol/ml L-carnitine, the plasma levels of free carnitine were not significantly different from those in infants receiving formula with 250 nmol/ml L-carnitine; however, urine levels of free carnitine were significantly increased when the infants received formula with 250 nmol/ml L-carnitine. In normal full-term infants, supplementation of soybean formula with 50 nmol/ml L-carnitine was sufficient to maintain normal plasma levels that were comparable to breast-fed infants.
| Original language | English |
|---|---|
| Pages (from-to) | 220-224 |
| Number of pages | 5 |
| Journal | Journal of Pediatric Gastroenterology and Nutrition |
| Volume | 7 |
| Issue number | 2 |
| State | Published - Mar 1 1988 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Food Science
- Medicine (miscellaneous)
- Gastroenterology
- Histology
- Pediatrics, Perinatology, and Child Health
Cite this
L-carnitine supplementation of a soybean-based formula in early infancy : plasma and urine levels of carnitine and acylcarnitines. / Novak, M.; Monkus, E. F.; Buch, M.; Silverio, J.; Clouston, O. M.; Cassady, J. C.
In: Journal of Pediatric Gastroenterology and Nutrition, Vol. 7, No. 2, 01.03.1988, p. 220-224.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - L-carnitine supplementation of a soybean-based formula in early infancy
T2 - plasma and urine levels of carnitine and acylcarnitines.
AU - Novak, M.
AU - Monkus, E. F.
AU - Buch, M.
AU - Silverio, J.
AU - Clouston, O. M.
AU - Cassady, J. C.
PY - 1988/3/1
Y1 - 1988/3/1
N2 - The absence of carnitine in the diet of normal infants results in marked reduction of plasma carnitine levels. In order to evaluate the effects of L-carnitine supplementation of soybean formula, plasma and urine levels of free carnitine and acylcarnitine were compared in infants receiving carnitine-free soybean protein-based formula and the same formula supplemented with 50 and 250 nmol/ml L-carnitine. In infants receiving soybean formula with 50 nmol/ml L-carnitine, the plasma levels of free carnitine were not significantly different from those in infants receiving formula with 250 nmol/ml L-carnitine; however, urine levels of free carnitine were significantly increased when the infants received formula with 250 nmol/ml L-carnitine. In normal full-term infants, supplementation of soybean formula with 50 nmol/ml L-carnitine was sufficient to maintain normal plasma levels that were comparable to breast-fed infants.
AB - The absence of carnitine in the diet of normal infants results in marked reduction of plasma carnitine levels. In order to evaluate the effects of L-carnitine supplementation of soybean formula, plasma and urine levels of free carnitine and acylcarnitine were compared in infants receiving carnitine-free soybean protein-based formula and the same formula supplemented with 50 and 250 nmol/ml L-carnitine. In infants receiving soybean formula with 50 nmol/ml L-carnitine, the plasma levels of free carnitine were not significantly different from those in infants receiving formula with 250 nmol/ml L-carnitine; however, urine levels of free carnitine were significantly increased when the infants received formula with 250 nmol/ml L-carnitine. In normal full-term infants, supplementation of soybean formula with 50 nmol/ml L-carnitine was sufficient to maintain normal plasma levels that were comparable to breast-fed infants.
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UR - http://www.scopus.com/inward/citedby.url?scp=0023973758&partnerID=8YFLogxK
M3 - Article
C2 - 3351707
AN - SCOPUS:0023973758
VL - 7
SP - 220
EP - 224
JO - Journal of Pediatric Gastroenterology and Nutrition
JF - Journal of Pediatric Gastroenterology and Nutrition
SN - 0277-2116
IS - 2
ER -