L-carnitine supplementation of a soybean-based formula in early infancy: plasma and urine levels of carnitine and acylcarnitines.

M. Novak, E. F. Monkus, M. Buch, J. Silverio, O. M. Clouston, J. C. Cassady

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

The absence of carnitine in the diet of normal infants results in marked reduction of plasma carnitine levels. In order to evaluate the effects of L-carnitine supplementation of soybean formula, plasma and urine levels of free carnitine and acylcarnitine were compared in infants receiving carnitine-free soybean protein-based formula and the same formula supplemented with 50 and 250 nmol/ml L-carnitine. In infants receiving soybean formula with 50 nmol/ml L-carnitine, the plasma levels of free carnitine were not significantly different from those in infants receiving formula with 250 nmol/ml L-carnitine; however, urine levels of free carnitine were significantly increased when the infants received formula with 250 nmol/ml L-carnitine. In normal full-term infants, supplementation of soybean formula with 50 nmol/ml L-carnitine was sufficient to maintain normal plasma levels that were comparable to breast-fed infants.

Original languageEnglish
Pages (from-to)220-224
Number of pages5
JournalJournal of Pediatric Gastroenterology and Nutrition
Volume7
Issue number2
StatePublished - Mar 1 1988
Externally publishedYes

Fingerprint

Carnitine
carnitine
infancy
Soybeans
urine
Urine
soybeans
Infant Formula
infant formulas
acylcarnitine
Soybean Proteins
soy protein
breasts
Breast

ASJC Scopus subject areas

  • Food Science
  • Medicine (miscellaneous)
  • Gastroenterology
  • Histology
  • Pediatrics, Perinatology, and Child Health

Cite this

L-carnitine supplementation of a soybean-based formula in early infancy : plasma and urine levels of carnitine and acylcarnitines. / Novak, M.; Monkus, E. F.; Buch, M.; Silverio, J.; Clouston, O. M.; Cassady, J. C.

In: Journal of Pediatric Gastroenterology and Nutrition, Vol. 7, No. 2, 01.03.1988, p. 220-224.

Research output: Contribution to journalArticle

Novak, M. ; Monkus, E. F. ; Buch, M. ; Silverio, J. ; Clouston, O. M. ; Cassady, J. C. / L-carnitine supplementation of a soybean-based formula in early infancy : plasma and urine levels of carnitine and acylcarnitines. In: Journal of Pediatric Gastroenterology and Nutrition. 1988 ; Vol. 7, No. 2. pp. 220-224.
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