Knocking down Disease with siRNAs

Derek M. Dykxhoorn, Judy Lieberman

Research output: Contribution to journalShort surveypeer-review

171 Scopus citations


Knocking down expression of disease-related genes using small interfering RNAs (siRNAs) has potential for treating a variety of illnesses. This Essay will examine the opportunities for harnessing RNA interference (RNAi) for therapy, as well as the obstacles and possible ways to circumvent them.

Original languageEnglish (US)
Pages (from-to)231-235
Number of pages5
Issue number2
StatePublished - Jul 28 2006
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)


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