Knocking down Disease with siRNAs

Derek M Dykxhoorn, Judy Lieberman

Research output: Contribution to journalArticle

162 Citations (Scopus)

Abstract

Knocking down expression of disease-related genes using small interfering RNAs (siRNAs) has potential for treating a variety of illnesses. This Essay will examine the opportunities for harnessing RNA interference (RNAi) for therapy, as well as the obstacles and possible ways to circumvent them.

Original languageEnglish
Pages (from-to)231-235
Number of pages5
JournalCell
Volume126
Issue number2
DOIs
StatePublished - Jul 28 2006
Externally publishedYes

Fingerprint

RNA Interference
Small Interfering RNA
Genes
RNA
Therapeutics

ASJC Scopus subject areas

  • Cell Biology
  • Molecular Biology

Cite this

Knocking down Disease with siRNAs. / Dykxhoorn, Derek M; Lieberman, Judy.

In: Cell, Vol. 126, No. 2, 28.07.2006, p. 231-235.

Research output: Contribution to journalArticle

Dykxhoorn, Derek M ; Lieberman, Judy. / Knocking down Disease with siRNAs. In: Cell. 2006 ; Vol. 126, No. 2. pp. 231-235.
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