Kit and melanocyte migration

James M Grichnik

Research output: Contribution to journalArticle

42 Citations (Scopus)

Abstract

As described in this issue, Alexeev and Yoon introduced a Kit-activating mutation into melanocytes. Although mitogenic in mast cells, this mutation was motogenic in melanocytes. Further, melanocytes had a reduced proliferative rate and were less differentiated. The disparate response may be due to differences in the cellular milieu of melanocytes and may have implications for normal melanocytic integration into the epidermis, nevogenesis, and melanoma.

Original languageEnglish
Pages (from-to)945-947
Number of pages3
JournalJournal of Investigative Dermatology
Volume126
Issue number5
DOIs
StatePublished - May 1 2006
Externally publishedYes

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Melanocytes
Mutation
Epidermis
Mast Cells
Melanoma

ASJC Scopus subject areas

  • Dermatology

Cite this

Kit and melanocyte migration. / Grichnik, James M.

In: Journal of Investigative Dermatology, Vol. 126, No. 5, 01.05.2006, p. 945-947.

Research output: Contribution to journalArticle

Grichnik, James M. / Kit and melanocyte migration. In: Journal of Investigative Dermatology. 2006 ; Vol. 126, No. 5. pp. 945-947.
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