JT dispersion in Wolff-Parkinson-White syndrome

Effect of eccentric ventricular depolarization on the dispersion of repolarization

Seshadri Balaji, Mary C Sokoloski, Christopher L. Case, Paul C. Gillette

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

There is much interest in QT dispersion for noninvasive risk stratification of patients at risk of arrhythmias. However, little is known about the genesis of abnormal QT dispersion. In particular, whether eccentric ventricular depolarization, as seen in preexcitation, can lead to abnormal dispersion of repolarization is unknown. We studied 24 children aged 1-19 years (mean ± SD, 11 ± 5 years) with manifest preexcitation due to Wolff- Parkinson-White syndrome who had successful catheter ablation. Standard ECGs done preablation, early postablation (< 1 week), mid postablation (> 1 week, < 2 months), and late postablation (> 2 months) were reviewed. The QBS duration prior to ablation ranged from 90-160 ms (mean ± SD, 123 ± 21 ms). On the preablation ECG, the JT and JTc dispersions showed no relationship to the QBS duration (r = 0.04 and 0.07, respectively). There was no change in JT dispersion when the preablation (42 ± 15 ms) ECG was compared to early (43 ± 15 ms), mid (44 ± 13 ms), and late postablation (48 ± 19 ms) ECGs. There was no significant change in JTc dispersion as well. Thus, JT dispersion is unrelated to QBS duration and unaffected by catheter ablation in patients with Wolff-Parkinson-White syndrome. Eccentric ventricular depolarization does not lead to abnormal dispersion of repolarization.

Original languageEnglish
Pages (from-to)576-579
Number of pages4
JournalPACE - Pacing and Clinical Electrophysiology
Volume21
Issue number3
DOIs
StatePublished - Apr 22 1998
Externally publishedYes

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Wolff-Parkinson-White Syndrome
Electrocardiography
Catheter Ablation
Cardiac Arrhythmias

Keywords

  • Catheter ablation
  • JT dispersion
  • Preexcitation
  • Ventricular repolarization

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

JT dispersion in Wolff-Parkinson-White syndrome : Effect of eccentric ventricular depolarization on the dispersion of repolarization. / Balaji, Seshadri; Sokoloski, Mary C; Case, Christopher L.; Gillette, Paul C.

In: PACE - Pacing and Clinical Electrophysiology, Vol. 21, No. 3, 22.04.1998, p. 576-579.

Research output: Contribution to journalArticle

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