Joint attention studies in normal and autistic children using NIRS

Ujwal Chaudhary, Michael Hall, Anibal Gutierrez, Daniel S Messinger, Gustavo Rey, Anuradha Godavarty

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Citations (Scopus)

Abstract

Autism is a socio-communication brain development disorder. It is marked by degeneration in the ability to respond to joint attention skill task, from as early as 12 to 18 months of age. This trait is used to distinguish autistic from nonautistic. In this study Near infrared spectroscopy (NIRS) is being applied for the first time to study the difference in activation and connectivity in the frontal cortex of typically developing (TD) and autistic children between 4-8 years of age in response to joint attention task. The optical measurements are acquired in real time from frontal cortex using Imagent (ISS Inc.) - a frequency domain based NIRS system in response to video clips which engenders a feeling of joint attention experience in the subjects. A block design consisting of 5 blocks of following sequence 30 sec joint attention clip (J), 30 sec non-joint attention clip (NJ) and 30 sec rest condition is used. Preliminary results from TD child shows difference in brain activation (in terms of oxy-hemoglobin, HbO) during joint attention interaction compared to the nonjoint interaction and rest. Similar activation study did not reveal significant differences in HbO across the stimuli in, unlike in an autistic child. Extensive studies are carried out to validate the initial observations from both brain activation as well as connectivity analysis. The result has significant implication for research in neural pathways associated with autism that can be mapped using NIRS.

Original languageEnglish
Title of host publicationProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume7883
DOIs
StatePublished - Apr 12 2011
EventPhotonic Therapeutics and Diagnostics VII - San Francisco, CA, United States
Duration: Jan 22 2011Jan 24 2011

Other

OtherPhotonic Therapeutics and Diagnostics VII
CountryUnited States
CitySan Francisco, CA
Period1/22/111/24/11

Fingerprint

Near infrared spectroscopy
Near-Infrared Spectroscopy
Brain
Chemical activation
infrared spectroscopy
clips
Surgical Instruments
activation
Activation analysis
brain
cortexes
Hemoglobin
Frontal Lobe
Autistic Disorder
Hemoglobins
oxyhemoglobin
sensory feedback
Neural Pathways
Aptitude
degeneration

Keywords

  • Autism
  • Autism Spectrum Disorders (ASD)
  • Brain Activation
  • Hemodynamic Changes
  • Joint Attention
  • Near Infrared Spectroscopy
  • Typically Developing (TD)

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

Cite this

Chaudhary, U., Hall, M., Gutierrez, A., Messinger, D. S., Rey, G., & Godavarty, A. (2011). Joint attention studies in normal and autistic children using NIRS. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE (Vol. 7883). [788348] https://doi.org/10.1117/12.874360

Joint attention studies in normal and autistic children using NIRS. / Chaudhary, Ujwal; Hall, Michael; Gutierrez, Anibal; Messinger, Daniel S; Rey, Gustavo; Godavarty, Anuradha.

Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 7883 2011. 788348.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Chaudhary, U, Hall, M, Gutierrez, A, Messinger, DS, Rey, G & Godavarty, A 2011, Joint attention studies in normal and autistic children using NIRS. in Progress in Biomedical Optics and Imaging - Proceedings of SPIE. vol. 7883, 788348, Photonic Therapeutics and Diagnostics VII, San Francisco, CA, United States, 1/22/11. https://doi.org/10.1117/12.874360
Chaudhary U, Hall M, Gutierrez A, Messinger DS, Rey G, Godavarty A. Joint attention studies in normal and autistic children using NIRS. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 7883. 2011. 788348 https://doi.org/10.1117/12.874360
Chaudhary, Ujwal ; Hall, Michael ; Gutierrez, Anibal ; Messinger, Daniel S ; Rey, Gustavo ; Godavarty, Anuradha. / Joint attention studies in normal and autistic children using NIRS. Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 7883 2011.
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