Itch associated with dryness of the skin: The pathophysiology and influence of moisturizers

Brett T. Summey, Gil Yosipovitch

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations


Xeroderma (dry skin) is characterized by a scaly, rough, cracked, and fissured surface, and is intimately associated with the somatosensory sensation of itch. Nearly every dermatological condition that manifests with xerotic skin is accompanied by itch. Atopic dermatitis is the hallmark and most prevalent of the conditions manifesting with dry skin and itch. Other clinical conditions involving dry skin and pruritus include common diseases like psoriasis, seasonal xerosis, pruritus of the elderly, asteatotic eczema, certain ichythoses, as well as systemic diseases such as uremia and human immunodeficiency virus infection. Quite interestingly, patients with ichythosis vulgaris, which is associated with significant xerosis, do not complain of itch.

Original languageEnglish (US)
Title of host publicationDry Skin and Moisturizers
Subtitle of host publicationChemistry and Function, Second Edition
PublisherCRC Press
Number of pages7
ISBN (Electronic)9781420039214
ISBN (Print)0849321344, 9780849321344
StatePublished - Jan 1 2005
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)


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