Itch

Gil Yosipovitch, Malcolm W. Greaves, Martin Schmelz

Research output: Contribution to journalReview article

298 Scopus citations

Abstract

Itch is a common skin sensation, with substantial effects on behaviour. Neurophysiological research has permitted accurate definition of neural pathways of itch, and has confirmed the distinctiveness of itch pathways in comparison with pain. A clinical classification of itch, based on such improved understanding, describes the difference between peripheral (pruritoceptive) and central (neurogenic or neuropathic) itch. New specific and sensitive investigational methods in people and animals enable us to better understand this bothersome symptom, and have important clinical implications. We describe the clinical classification of itch, new findings on neuropathophysiology of itch, methods for assessment, and improved treatments.

Original languageEnglish (US)
Pages (from-to)690-694
Number of pages5
JournalLancet
Volume361
Issue number9358
DOIs
StatePublished - Feb 22 2003
Externally publishedYes

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ASJC Scopus subject areas

  • Medicine(all)

Cite this

Yosipovitch, G., Greaves, M. W., & Schmelz, M. (2003). Itch. Lancet, 361(9358), 690-694. https://doi.org/10.1016/S0140-6736(03)12570-6