Isotope-edited FTIR in H2O: Determination of the conformation of specific residues in a model α-helix peptide by 13C labeled carbonyls

Shanghao Li, Sneha Potana, Donnan J. Keith, Chengshan Wang, Roger M. Leblanc

Research output: Contribution to journalArticle

8 Scopus citations

Abstract

Isotope-edited FTIR spectroscopy has been shown to be able to determine peptide's structure in the residue level in D2O, which is not a physiological solvent. Here, attenuated total reflection technique was utilized to successfully apply isotope-edited FTIR spectroscopy in H2O to determine the conformation of specific residues in a model peptide.

Original languageEnglish (US)
Pages (from-to)3931-3933
Number of pages3
JournalChemical Communications
Volume50
Issue number31
DOIs
StatePublished - Mar 20 2014

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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