Isolation of Actinomyces species and Eikenella corrodens from patients with chronic diffuse sclerosing osteomyelitis

Robert E. Marx, Eric R. Carlson, Brian R. Smith, Norma Toraya

Research output: Contribution to journalArticle

61 Scopus citations


Cultures from 26 patients with chronic diffuse sclerosing osteomyelitis of the mandible were studied. In most cases there was a mutualistic infection involving any one of the known human Actinomyces species together with Eikenella corrodens. In a few cases, Arachnia species were substituted for Actinomyces and gram-negative anaerobes for E corrodens. The specific culture protocol used to identify these organisms from clinical specimens is described. Taxonomic and experimental evidence that supports and infectious etiology are presented.

Original languageEnglish (US)
Pages (from-to)26-33
Number of pages8
JournalJournal of Oral and Maxillofacial Surgery
Issue number1
StatePublished - Jan 1994
Externally publishedYes


ASJC Scopus subject areas

  • Surgery
  • Oral Surgery
  • Otorhinolaryngology

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