Ischaemic conditioning and targeting reperfusion injury: a 30 year voyage of discovery

Derek J. Hausenloy, Jose A. Barrabes, Hans Erik Bøtker, Sean M. Davidson, Fabio Di Lisa, James Downey, Thomas Engstrom, Péter Ferdinandy, Hector A. Carbrera-Fuentes, Gerd Heusch, Borja Ibanez, Efstathios K. Iliodromitis, Javier Inserte, Robert Jennings, Neena Kalia, Rajesh Kharbanda, Sandrine Lecour, Michael Marber, Tetsuji Miura, Michel OvizeMiguel A. Perez-Pinzon, Hans Michael Piper, Karin Przyklenk, Michael Rahbek Schmidt, Andrew Redington, Marisol Ruiz-Meana, Gemma Vilahur, Jakob Vinten-Johansen, Derek M. Yellon, David Garcia-Dorado

Research output: Contribution to journalReview article

131 Scopus citations

Abstract

To commemorate the auspicious occasion of the 30th anniversary of IPC, leading pioneers in the field of cardioprotection gathered in Barcelona in May 2016 to review and discuss the history of IPC, its evolution to IPost and RIC, myocardial reperfusion injury as a therapeutic target, and future targets and strategies for cardioprotection. This article provides an overview of the major topics discussed at this special meeting and underscores the huge importance and impact, the discovery of IPC has made in the field of cardiovascular research.

Original languageEnglish (US)
Article number70
JournalBasic Research in Cardiology
Volume111
Issue number6
DOIs
StatePublished - Nov 1 2016

Keywords

  • Cardioprotection
  • Ischaemic conditioning
  • Mitochondria
  • Myocardial reperfusion injury
  • RISK and SAFE pathway

ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)

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  • Cite this

    Hausenloy, D. J., Barrabes, J. A., Bøtker, H. E., Davidson, S. M., Di Lisa, F., Downey, J., Engstrom, T., Ferdinandy, P., Carbrera-Fuentes, H. A., Heusch, G., Ibanez, B., Iliodromitis, E. K., Inserte, J., Jennings, R., Kalia, N., Kharbanda, R., Lecour, S., Marber, M., Miura, T., ... Garcia-Dorado, D. (2016). Ischaemic conditioning and targeting reperfusion injury: a 30 year voyage of discovery. Basic Research in Cardiology, 111(6), [70]. https://doi.org/10.1007/s00395-016-0588-8