TY - JOUR
T1 - Ischaemic conditioning and targeting reperfusion injury
T2 - a 30 year voyage of discovery
AU - Hausenloy, Derek J.
AU - Barrabes, Jose A.
AU - Bøtker, Hans Erik
AU - Davidson, Sean M.
AU - Di Lisa, Fabio
AU - Downey, James
AU - Engstrom, Thomas
AU - Ferdinandy, Péter
AU - Carbrera-Fuentes, Hector A.
AU - Heusch, Gerd
AU - Ibanez, Borja
AU - Iliodromitis, Efstathios K.
AU - Inserte, Javier
AU - Jennings, Robert
AU - Kalia, Neena
AU - Kharbanda, Rajesh
AU - Lecour, Sandrine
AU - Marber, Michael
AU - Miura, Tetsuji
AU - Ovize, Michel
AU - Perez-Pinzon, Miguel A.
AU - Piper, Hans Michael
AU - Przyklenk, Karin
AU - Schmidt, Michael Rahbek
AU - Redington, Andrew
AU - Ruiz-Meana, Marisol
AU - Vilahur, Gemma
AU - Vinten-Johansen, Jakob
AU - Yellon, Derek M.
AU - Garcia-Dorado, David
N1 - Funding Information:
DJH was funded by the British Heart Foundation (Grant Number FS/10/039/28270), the Rosetrees Trust, and is supported by the National Institute for Health Research University College London Hospitals Biomedical Research Centre. HEB was funded by the Danish Council for Independent Research (11-108354), the Danish Council for Strategic Research (11-115818), the Novo-Nordisk Foundation and Trygfonden. PF was funded by the Hungarian Scientific Research Fund (OTKA K 109737 and ANN 107803). HACF is funded by a Startup Grant of the “Excellence Cluster Cardio-Pulmonary System” (ECCPS) from the German Research Foundation (DFG, Bonn, Germany) and the “Peter und Traudl Engelhorn-Stiftung” (Weilheim, Germany) and in part by the Russian Government Program for competitive growth of Kazan Federal University, Kazan (Russian Federation). GH was supported by the German Research Foundation (He 1320/18-3 and SFB 1116/B8). TM was funded by the Japan Society for the Promotion of Science (Grant-in-Aid for Scientific Research #23591086, #2646113). MRS was funded by Novo-Nordisk Foundation. DG-D is supported by the Spanish Institute of Health, Instituto de Salud Carlos III (Grants PIE 13/00027, RETICS-RIC, RD12/0042/0021, and PI14/01431). RS and PF were funded by the European Foundation for the Study of Diabetes (EFSD) New Horizons Collaborative Research Initiative from the European Association for the Study of Diabetes (EASD) and by the European Cooperation in Science and Technology (COST EU-ROS). PF was funded by the Hungarian Scientific Research Fund (OTKA K 109737 and ANN 107803).
Publisher Copyright:
© 2016, The Author(s).
PY - 2016/11/1
Y1 - 2016/11/1
N2 - To commemorate the auspicious occasion of the 30th anniversary of IPC, leading pioneers in the field of cardioprotection gathered in Barcelona in May 2016 to review and discuss the history of IPC, its evolution to IPost and RIC, myocardial reperfusion injury as a therapeutic target, and future targets and strategies for cardioprotection. This article provides an overview of the major topics discussed at this special meeting and underscores the huge importance and impact, the discovery of IPC has made in the field of cardiovascular research.
AB - To commemorate the auspicious occasion of the 30th anniversary of IPC, leading pioneers in the field of cardioprotection gathered in Barcelona in May 2016 to review and discuss the history of IPC, its evolution to IPost and RIC, myocardial reperfusion injury as a therapeutic target, and future targets and strategies for cardioprotection. This article provides an overview of the major topics discussed at this special meeting and underscores the huge importance and impact, the discovery of IPC has made in the field of cardiovascular research.
KW - Cardioprotection
KW - Ischaemic conditioning
KW - Mitochondria
KW - Myocardial reperfusion injury
KW - RISK and SAFE pathway
UR - http://www.scopus.com/inward/record.url?scp=84991769840&partnerID=8YFLogxK
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U2 - 10.1007/s00395-016-0588-8
DO - 10.1007/s00395-016-0588-8
M3 - Review article
C2 - 27766474
AN - SCOPUS:84991769840
VL - 111
JO - Basic Research in Cardiology
JF - Basic Research in Cardiology
SN - 0300-8428
IS - 6
M1 - 70
ER -