Is there a special relationship between CD30-positive lymphoproliferative disorders and epidermal proliferation?

Yvana P. Cespedes, Paul F. Rockley, Frank Flores, Phillip Ruiz, Mark R. Kaiser, George W. Elgart

Research output: Contribution to journalArticle

30 Scopus citations

Abstract

The relationship between CD30 + lymphoma and epithelial proliferations is not well defined. CD30 + lymphoma and lymphomatoid papulos (LyP) share immunohistochemical epitopes and some other features. A single case of LyP associated with multiple keratoacanthomas (KAs) was recently reported. We report two cases of atypical lymphocytic proliferation with features of CD30 + lymphoma and LyP intimately associated to KA and squamous cell carcinoma (SCC), KA type. This similar combination of an epidermal tumor and apparent involvement with atypical lymphocytic infiltrates raises the possibility of an association between the two entities. We speculate that the association may be more than expected to occur by chance and suggest several mechanisms by which the association may evolve. (C) Munksgaard 2000.

Original languageEnglish (US)
Pages (from-to)271-275
Number of pages5
JournalJournal of Cutaneous Pathology
Volume27
Issue number6
DOIs
StatePublished - Jun 30 2000

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology
  • Dermatology

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