Is all ventricular fibrillation the same? Influence of mode of induction on characteristics of ventricular fibrillation

Taresh Taneja, Jeffrey Goldberger, David Johnson, Alan Kadish

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

Characteristics of Induced VF. Introduction: Little information is available on the relationship between the mode of induction of ventricular fibrillation (VF) to VF characteristics. Methods and Results: VF was induced from the anterior left ventricle by programmed electrical stimulation, burst pacing, alternating current (AC), high current S2 at a site remote from S1, T wave shock, and intersecting wavefronts in seven normal dogs and seven dogs with chronic myocardial infarction. Using two electrode arrays, 112 electrograms were recorded from the anterior and lateral wall. Cycle lengths were analyzed and activation vectors were created by summing orthogonally recorded bipolar electrograms. The magnitude of the vector loops was integrated over time to produce an "ensemble vector" index (EVI) whose magnitude is high when beat-to-beat activation direction is consistent and low when activation direction is variable. T wave shack-induced VF had a significantly longer cycle length 1 to 5 seconds after VF onset than other modes of induction (P < 0.05). The frequency-corrected EVI was significantly larger for AC current and T wave shock-induced VF as opposed to all other modes of VF induction in early VF (P < 0.0001). After 10 seconds of VF, these differences persisted only on the anterior wall. Conclusion: VF induced in animals by T wave shock and AC current had different characteristics than VF induced by other methods. These findings may have implications for our understanding of VF pathophysiology.

Original languageEnglish (US)
Pages (from-to)1355-1363
Number of pages9
JournalJournal of Cardiovascular Electrophysiology
Volume11
Issue number12
DOIs
StatePublished - Jan 1 2000
Externally publishedYes

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Ventricular Fibrillation
Shock
Dogs
Electric Stimulation
Heart Ventricles
Electrodes
Myocardial Infarction

Keywords

  • Fibrillation
  • Induction
  • Ventricles

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)

Cite this

Is all ventricular fibrillation the same? Influence of mode of induction on characteristics of ventricular fibrillation. / Taneja, Taresh; Goldberger, Jeffrey; Johnson, David; Kadish, Alan.

In: Journal of Cardiovascular Electrophysiology, Vol. 11, No. 12, 01.01.2000, p. 1355-1363.

Research output: Contribution to journalArticle

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