Irreversible Electroporation in the Treatment of Hepatocellular Carcinoma

Riccardo Lencioni, Laura Crocetti, Govindarajan Narayanan

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


Irreversible electroporation (IRE) is a new nonthermal ablation modality that can be used to treat primary and metastatic lesions in the liver. This article describes the way IRE works, reviews safety and efficacy data, and presents strategies and recommendations for its use in everyday practice. In a series of liver lesions of various histologies, initial success was 100%; local recurrence rates were greater in larger lesions. In another series of hepatocellular carcinoma only, there was a 79% complete response rate overall and 93% in lesions less than 3. cm. Safety is comparable with those of other ablation modalities. IRE has advantages over other ablation modalities with comparable success rates.

Original languageEnglish (US)
Pages (from-to)135-139
Number of pages5
JournalTechniques in Vascular and Interventional Radiology
Issue number3
StatePublished - Sep 1 2015


  • Hepatocellular carcinoma
  • Image-guided ablation
  • Irreversible electroporation

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine


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