Ion-selective microelectrodes suitable for recording rapid changes in extracellular ion concentration

Rong Wen, Burks Oakley

Research output: Contribution to journalArticle

19 Scopus citations

Abstract

A method for fabricating double-barrel, ion-selective microelectrodes with fine tips (0.5-1.5 μm) and rapid response times is described. When made into K+-selective microelectrodes, the electrodes respond to changes in [K+]o with a time constant of 70-95 ms. The electrical response of these electrodes to common-mode voltages can be made to have a time constant of < 2 ms, which minimizes electrical artifacts from field potentials. The application of these microelectrodes to the measurement of rapid, transient changes in retinal [K+]o is presented.

Original languageEnglish (US)
Pages (from-to)207-213
Number of pages7
JournalJournal of Neuroscience Methods
Volume31
Issue number3
DOIs
StatePublished - Mar 1990

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Keywords

  • Electroretinogram b-wave
  • Extracellular potassium
  • K-selective microelectrode
  • Vertebrate retina

ASJC Scopus subject areas

  • Neuroscience(all)

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