TY - JOUR
T1 - Ion-selective microelectrodes suitable for recording rapid changes in extracellular ion concentration
AU - Wen, Rong
AU - Oakley, Burks
PY - 1990/3
Y1 - 1990/3
N2 - A method for fabricating double-barrel, ion-selective microelectrodes with fine tips (0.5-1.5 μm) and rapid response times is described. When made into K+-selective microelectrodes, the electrodes respond to changes in [K+]o with a time constant of 70-95 ms. The electrical response of these electrodes to common-mode voltages can be made to have a time constant of < 2 ms, which minimizes electrical artifacts from field potentials. The application of these microelectrodes to the measurement of rapid, transient changes in retinal [K+]o is presented.
AB - A method for fabricating double-barrel, ion-selective microelectrodes with fine tips (0.5-1.5 μm) and rapid response times is described. When made into K+-selective microelectrodes, the electrodes respond to changes in [K+]o with a time constant of 70-95 ms. The electrical response of these electrodes to common-mode voltages can be made to have a time constant of < 2 ms, which minimizes electrical artifacts from field potentials. The application of these microelectrodes to the measurement of rapid, transient changes in retinal [K+]o is presented.
KW - Electroretinogram b-wave
KW - Extracellular potassium
KW - K-selective microelectrode
KW - Vertebrate retina
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U2 - 10.1016/0165-0270(90)90112-S
DO - 10.1016/0165-0270(90)90112-S
M3 - Article
C2 - 2329840
AN - SCOPUS:0025008903
VL - 31
SP - 207
EP - 213
JO - Journal of Neuroscience Methods
JF - Journal of Neuroscience Methods
SN - 0165-0270
IS - 3
ER -