Abstract
A method for fabricating double-barrel, ion-selective microelectrodes with fine tips (0.5-1.5 μm) and rapid response times is described. When made into K+-selective microelectrodes, the electrodes respond to changes in [K+]o with a time constant of 70-95 ms. The electrical response of these electrodes to common-mode voltages can be made to have a time constant of < 2 ms, which minimizes electrical artifacts from field potentials. The application of these microelectrodes to the measurement of rapid, transient changes in retinal [K+]o is presented.
| Original language | English |
|---|---|
| Pages (from-to) | 207-213 |
| Number of pages | 7 |
| Journal | Journal of Neuroscience Methods |
| Volume | 31 |
| Issue number | 3 |
| DOIs | |
| State | Published - Jan 1 1990 |
| Externally published | Yes |
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Keywords
- Electroretinogram b-wave
- Extracellular potassium
- K-selective microelectrode
- Vertebrate retina
ASJC Scopus subject areas
- Neuroscience(all)
Cite this
Ion-selective microelectrodes suitable for recording rapid changes in extracellular ion concentration. / Wen, Rong; Oakley, Burks.
In: Journal of Neuroscience Methods, Vol. 31, No. 3, 01.01.1990, p. 207-213.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Ion-selective microelectrodes suitable for recording rapid changes in extracellular ion concentration
AU - Wen, Rong
AU - Oakley, Burks
PY - 1990/1/1
Y1 - 1990/1/1
N2 - A method for fabricating double-barrel, ion-selective microelectrodes with fine tips (0.5-1.5 μm) and rapid response times is described. When made into K+-selective microelectrodes, the electrodes respond to changes in [K+]o with a time constant of 70-95 ms. The electrical response of these electrodes to common-mode voltages can be made to have a time constant of < 2 ms, which minimizes electrical artifacts from field potentials. The application of these microelectrodes to the measurement of rapid, transient changes in retinal [K+]o is presented.
AB - A method for fabricating double-barrel, ion-selective microelectrodes with fine tips (0.5-1.5 μm) and rapid response times is described. When made into K+-selective microelectrodes, the electrodes respond to changes in [K+]o with a time constant of 70-95 ms. The electrical response of these electrodes to common-mode voltages can be made to have a time constant of < 2 ms, which minimizes electrical artifacts from field potentials. The application of these microelectrodes to the measurement of rapid, transient changes in retinal [K+]o is presented.
KW - Electroretinogram b-wave
KW - Extracellular potassium
KW - K-selective microelectrode
KW - Vertebrate retina
UR - http://www.scopus.com/inward/record.url?scp=0025008903&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0025008903&partnerID=8YFLogxK
U2 - 10.1016/0165-0270(90)90112-S
DO - 10.1016/0165-0270(90)90112-S
M3 - Article
VL - 31
SP - 207
EP - 213
JO - Journal of Neuroscience Methods
JF - Journal of Neuroscience Methods
SN - 0165-0270
IS - 3
ER -