Abstract
A method for fabricating double-barrel, ion-selective microelectrodes with fine tips (0.5-1.5 μm) and rapid response times is described. When made into K+-selective microelectrodes, the electrodes respond to changes in [K+]o with a time constant of 70-95 ms. The electrical response of these electrodes to common-mode voltages can be made to have a time constant of < 2 ms, which minimizes electrical artifacts from field potentials. The application of these microelectrodes to the measurement of rapid, transient changes in retinal [K+]o is presented.
Original language | English (US) |
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Pages (from-to) | 207-213 |
Number of pages | 7 |
Journal | Journal of Neuroscience Methods |
Volume | 31 |
Issue number | 3 |
DOIs | |
State | Published - Mar 1990 |
Externally published | Yes |
Keywords
- Electroretinogram b-wave
- Extracellular potassium
- K-selective microelectrode
- Vertebrate retina
ASJC Scopus subject areas
- Neuroscience(all)