Involvement of USP24 in the DNA damage response

Ling Zhang, Feng Gong

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

Deubiquitination has emerged as an important mechanism of regulating DNA repair pathways. We recently reported that USP24 is a novel p53 deubiquitinase that stabilizes p53 upon DNA damage. USP24 is upregulated by DNA damaging agents and plays an important role in maintaining genome stability.

Original languageEnglish (US)
Article numbere1011888
JournalMolecular and Cellular Oncology
Volume3
Issue number1
DOIs
StatePublished - Jan 2 2016

Keywords

  • DNA damage response
  • USP24
  • deubiquitinase
  • deubiquitination
  • p53

ASJC Scopus subject areas

  • Molecular Medicine
  • Cancer Research

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