Invasive pneumonia and septic shock in infants as a presentation of cystic fibrosis with vitamin-deficiency

Eman S. Al-Khadra, Kin Wai Chau, Cara Pizzo Barone, Andrew A. Colin

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Herein we describe three infants with the rare presentation of pneumonia with septic shock as their initial medical encounter leading to the diagnosis of cystic fibrosis (CF). At the time of their presentation all three children had significant nutritional deficiency. We initiated an aggressive treatment regimen including nutritional supplementation which resulted in improvement in their pulmonary status and no further recurrences. This series highlights the possible presentation of CF in infancy as a life-threatening invasive infection of Staphylococcus aureus or Pseudomonas aeruginosa. It also supports neonatal screening and emphasizes the role of early attention to nutritional status and vitamin supplementation. Pediatr Pulmonol. 2012; 47:722-726.

Original languageEnglish (US)
Pages (from-to)722-726
Number of pages5
JournalPediatric pulmonology
Issue number7
StatePublished - Jul 2012


  • bacteremia
  • cystic fibrosis
  • pneumonia
  • Pseudomonas aeruginosa
  • sepsis
  • Staphylococcus aureus
  • vitamin D
  • vitamin deficiency

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Pulmonary and Respiratory Medicine


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